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Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation.
Staus DP, Strachan RT, Manglik A, Pani B, Kahsai AW, Kim TH, Wingler LM, Ahn S, Chatterjee A, Masoudi A, Kruse AC, Pardon E, Steyaert J, Weis WI, Prosser RS, Kobilka BK, Costa T, Lefkowitz RJ. Staus DP, et al. Among authors: kim th. Nature. 2016 Jul 21;535(7612):448-52. doi: 10.1038/nature18636. Epub 2016 Jul 13. Nature. 2016. PMID: 27409812 Free PMC article.
Structural Insights into the Dynamic Process of β2-Adrenergic Receptor Signaling.
Manglik A, Kim TH, Masureel M, Altenbach C, Yang Z, Hilger D, Lerch MT, Kobilka TS, Thian FS, Hubbell WL, Prosser RS, Kobilka BK. Manglik A, et al. Among authors: kim th. Cell. 2015 May 21;161(5):1101-1111. doi: 10.1016/j.cell.2015.04.043. Epub 2015 May 14. Cell. 2015. PMID: 25981665 Free PMC article.
Substrate-Based Allosteric Regulation of a Homodimeric Enzyme.
Mehrabi P, Di Pietrantonio C, Kim TH, Sljoka A, Taverner K, Ing C, Kruglyak N, Pomès R, Pai EF, Prosser RS. Mehrabi P, et al. Among authors: kim th. J Am Chem Soc. 2019 Jul 24;141(29):11540-11556. doi: 10.1021/jacs.9b03703. Epub 2019 Jun 26. J Am Chem Soc. 2019. PMID: 31188575
7,189 results