Jo H - Search Results

1

Structural Polymorphism of Alzheimer's β-Amyloid Fibrils as Controlled by an E22 Switch: A Solid-State NMR Study.

Elkins MR, Wang T, Nick M, Jo H, Lemmin T, Prusiner SB, DeGrado WF, Stöhr J, Hong M. Elkins MR, et al. Among authors: jo h. J Am Chem Soc. 2016 Aug 10;138(31):9840-52. doi: 10.1021/jacs.6b03715. Epub 2016 Jul 28. J Am Chem Soc. 2016. PMID: 27414264 Free PMC article.

2

Selective incorporation of nitrile-based infrared probes into proteins via cysteine alkylation.

Jo H, Culik RM, Korendovych IV, Degrado WF, Gai F. Jo H, et al. Biochemistry. 2010 Dec 14;49(49):10354-6. doi: 10.1021/bi101711a. Epub 2010 Nov 17. Biochemistry. 2010. PMID: 21077670 Free PMC article.

3

Affinity of talin-1 for the β3-integrin cytosolic domain is modulated by its phospholipid bilayer environment.

Moore DT, Nygren P, Jo H, Boesze-Battaglia K, Bennett JS, DeGrado WF. Moore DT, et al. Among authors: jo h. Proc Natl Acad Sci U S A. 2012 Jan 17;109(3):793-8. doi: 10.1073/pnas.1117220108. Epub 2011 Dec 30. Proc Natl Acad Sci U S A. 2012. PMID: 22210111 Free PMC article.

4

Inhibition of integrin α2β1 ameliorates glomerular injury.

Borza CM, Su Y, Chen X, Yu L, Mont S, Chetyrkin S, Voziyan P, Hudson BG, Billings PC, Jo H, Bennett JS, Degrado WF, Eckes B, Zent R, Pozzi A. Borza CM, et al. Among authors: jo h. J Am Soc Nephrol. 2012 Jun;23(6):1027-38. doi: 10.1681/ASN.2011040367. Epub 2012 Mar 22. J Am Soc Nephrol. 2012. PMID: 22440900 Free PMC article.

5

Using thioamides to site-specifically interrogate the dynamics of hydrogen bond formation in β-sheet folding.

Culik RM, Jo H, DeGrado WF, Gai F. Culik RM, et al. Among authors: jo h. J Am Chem Soc. 2012 May 16;134(19):8026-9. doi: 10.1021/ja301681v. Epub 2012 May 2. J Am Chem Soc. 2012. PMID: 22540162 Free PMC article.

6

Development of α-helical calpain probes by mimicking a natural protein-protein interaction.

Jo H, Meinhardt N, Wu Y, Kulkarni S, Hu X, Low KE, Davies PL, DeGrado WF, Greenbaum DC. Jo H, et al. J Am Chem Soc. 2012 Oct 24;134(42):17704-13. doi: 10.1021/ja307599z. Epub 2012 Oct 11. J Am Chem Soc. 2012. PMID: 22998171 Free PMC article.

7

Discovery of novel dual inhibitors of the wild-type and the most prevalent drug-resistant mutant, S31N, of the M2 proton channel from influenza A virus.

Wang J, Ma C, Wang J, Jo H, Canturk B, Fiorin G, Pinto LH, Lamb RA, Klein ML, DeGrado WF. Wang J, et al. Among authors: jo h. J Med Chem. 2013 Apr 11;56(7):2804-12. doi: 10.1021/jm301538e. Epub 2013 Mar 27. J Med Chem. 2013. PMID: 23437766 Free PMC article.

8

Assessment of local friction in protein folding dynamics using a helix cross-linker.

Markiewicz BN, Jo H, Culik RM, DeGrado WF, Gai F. Markiewicz BN, et al. Among authors: jo h. J Phys Chem B. 2013 Nov 27;117(47):14688-96. doi: 10.1021/jp409334h. Epub 2013 Nov 18. J Phys Chem B. 2013. PMID: 24205975 Free PMC article.

9

Flipping in the pore: discovery of dual inhibitors that bind in different orientations to the wild-type versus the amantadine-resistant S31N mutant of the influenza A virus M2 proton channel.

Wu Y, Canturk B, Jo H, Ma C, Gianti E, Klein ML, Pinto LH, Lamb RA, Fiorin G, Wang J, DeGrado WF. Wu Y, et al. Among authors: jo h. J Am Chem Soc. 2014 Dec 31;136(52):17987-95. doi: 10.1021/ja508461m. Epub 2014 Dec 18. J Am Chem Soc. 2014. PMID: 25470189 Free PMC article.

10

The αvβ1 integrin plays a critical in vivo role in tissue fibrosis.

Reed NI, Jo H, Chen C, Tsujino K, Arnold TD, DeGrado WF, Sheppard D. Reed NI, et al. Among authors: jo h. Sci Transl Med. 2015 May 20;7(288):288ra79. doi: 10.1126/scitranslmed.aaa5094. Sci Transl Med. 2015. PMID: 25995225 Free PMC article.

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