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Inhibition of CBLB protects from lethal Candida albicans sepsis.
Wirnsberger G, Zwolanek F, Asaoka T, Kozieradzki I, Tortola L, Wimmer RA, Kavirayani A, Fresser F, Baier G, Langdon WY, Ikeda F, Kuchler K, Penninger JM. Wirnsberger G, et al. Among authors: kuchler k. Nat Med. 2016 Aug;22(8):915-23. doi: 10.1038/nm.4134. Epub 2016 Jul 18. Nat Med. 2016. PMID: 27428901 Free PMC article.
Jagunal homolog 1 is a critical regulator of neutrophil function in fungal host defense.
Wirnsberger G, Zwolanek F, Stadlmann J, Tortola L, Liu SW, Perlot T, Järvinen P, Dürnberger G, Kozieradzki I, Sarao R, De Martino A, Boztug K, Mechtler K, Kuchler K, Klein C, Elling U, Penninger JM. Wirnsberger G, et al. Among authors: kuchler k. Nat Genet. 2014 Sep;46(9):1028-33. doi: 10.1038/ng.3070. Epub 2014 Aug 17. Nat Genet. 2014. PMID: 25129145 Free PMC article.
The Candida albicans Histone Acetyltransferase Hat1 Regulates Stress Resistance and Virulence via Distinct Chromatin Assembly Pathways.
Tscherner M, Zwolanek F, Jenull S, Sedlazeck FJ, Petryshyn A, Frohner IE, Mavrianos J, Chauhan N, von Haeseler A, Kuchler K. Tscherner M, et al. Among authors: kuchler k. PLoS Pathog. 2015 Oct 16;11(10):e1005218. doi: 10.1371/journal.ppat.1005218. eCollection 2015 Oct. PLoS Pathog. 2015. PMID: 26473952 Free PMC article.
The histone chaperone HIR maintains chromatin states to control nitrogen assimilation and fungal virulence.
Jenull S, Mair T, Tscherner M, Penninger P, Zwolanek F, Silao FS, de San Vicente KM, Riedelberger M, Bandari NC, Shivarathri R, Petryshyn A, Chauhan N, Zacchi LF, -Landmann SL, Ljungdahl PO, Kuchler K. Jenull S, et al. Among authors: kuchler k. Cell Rep. 2021 Jul 20;36(3):109406. doi: 10.1016/j.celrep.2021.109406. Cell Rep. 2021. PMID: 34289370 Free PMC article.
177 results