O'Shea JJ - Search Results

1

Tofacitinib Ameliorates Murine Lupus and Its Associated Vascular Dysfunction.

Furumoto Y, Smith CK, Blanco L, Zhao W, Brooks SR, Thacker SG, Abdalrahman Z, Sciumè G, Tsai WL, Trier AM, Nunez L, Mast L, Hoffmann V, Remaley AT, O'Shea JJ, Kaplan MJ, Gadina M. Furumoto Y, et al. Arthritis Rheumatol. 2017 Jan;69(1):148-160. doi: 10.1002/art.39818. Arthritis Rheumatol. 2017. PMID: 27429362 Free PMC article.

2

IL-2, but not IL-4 and other cytokines, induces phosphorylation of a 98-kDa protein associated with SHP-2, phosphatidylinositol 3'-kinase, and Grb2.

Gadina M, Sudarshan C, O'Shea JJ. Gadina M, et al. J Immunol. 1999 Feb 15;162(4):2081-6. J Immunol. 1999. PMID: 9973481

3

Advances in cytokine signaling: the role of Jaks and STATs.

Chen E, Gadina M, Chen M, O'Shea JJ. Chen E, et al. Transplant Proc. 1999 May;31(3):1482-7. doi: 10.1016/s0041-1345(99)00013-5. Transplant Proc. 1999. PMID: 10330976 Review. No abstract available.

4

Jaks and stats as therapeutic targets.

O'Shea JJ, Visconti R, Cheng TP, Gadina M. O'Shea JJ, et al. Ann Rheum Dis. 2000 Nov;59 Suppl 1(Suppl 1):i115-8. doi: 10.1136/ard.59.suppl_1.i115. Ann Rheum Dis. 2000. PMID: 11053101 Free PMC article. Review.

5

Cytokine signaling in 2002: new surprises in the Jak/Stat pathway.

O'Shea JJ, Gadina M, Schreiber RD. O'Shea JJ, et al. Cell. 2002 Apr;109 Suppl:S121-31. doi: 10.1016/s0092-8674(02)00701-8. Cell. 2002. PMID: 11983158 Free article. Review.

6

Fyn kinase initiates complementary signals required for IgE-dependent mast cell degranulation.

Parravicini V, Gadina M, Kovarova M, Odom S, Gonzalez-Espinosa C, Furumoto Y, Saitoh S, Samelson LE, O'Shea JJ, Rivera J. Parravicini V, et al. Nat Immunol. 2002 Aug;3(8):741-8. doi: 10.1038/ni817. Epub 2002 Jul 1. Nat Immunol. 2002. PMID: 12089510

7

STAT4 serine phosphorylation is critical for IL-12-induced IFN-gamma production but not for cell proliferation.

Morinobu A, Gadina M, Strober W, Visconti R, Fornace A, Montagna C, Feldman GM, Nishikomori R, O'Shea JJ. Morinobu A, et al. Proc Natl Acad Sci U S A. 2002 Sep 17;99(19):12281-6. doi: 10.1073/pnas.182618999. Epub 2002 Sep 4. Proc Natl Acad Sci U S A. 2002. PMID: 12213961 Free PMC article.

8

Cytokines and transcription factors that regulate T helper cell differentiation: new players and new insights.

Agnello D, Lankford CS, Bream J, Morinobu A, Gadina M, O'Shea JJ, Frucht DM. Agnello D, et al. J Clin Immunol. 2003 May;23(3):147-61. doi: 10.1023/a:1023381027062. J Clin Immunol. 2003. PMID: 12797537 Review.

9

Cytokines and their role in lymphoid development, differentiation and homeostasis.

Hofmann SR, Ettinger R, Zhou YJ, Gadina M, Lipsky P, Siegel R, Candotti F, O'Shea JJ. Hofmann SR, et al. Curr Opin Allergy Clin Immunol. 2002 Dec;2(6):495-506. doi: 10.1097/00130832-200212000-00004. Curr Opin Allergy Clin Immunol. 2002. PMID: 14752332 Review.

10

CXCL12 signaling is independent of Jak2 and Jak3.

Moriguchi M, Hissong BD, Gadina M, Yamaoka K, Tiffany HL, Murphy PM, Candotti F, O'Shea JJ. Moriguchi M, et al. J Biol Chem. 2005 Apr 29;280(17):17408-14. doi: 10.1074/jbc.M414219200. Epub 2004 Dec 20. J Biol Chem. 2005. PMID: 15611059 Free article.

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