Harada A - Search Results

1

Is an in vitro whole blood cytokine assay useful to detect the potential risk of severe infusion reaction of monoclonal antibody pharmaceuticals?

Iwata Y, Harada A, Hara T, Kubo C, Inoue T, Tabo M, Ploix C, Manigold T, Hinton H, Mishima M. Iwata Y, et al. Among authors: harada a. J Toxicol Sci. 2016;41(4):523-31. doi: 10.2131/jts.41.523. J Toxicol Sci. 2016. PMID: 27432238 Free article.

2

A newly established GDL1 cell line from gpt delta mice well reflects the in vivo mutation spectra induced by mitomycin C.

Takeiri A, Mishima M, Tanaka K, Shioda A, Harada A, Watanabe K, Masumura K, Nohmi T. Takeiri A, et al. Among authors: harada a. Mutat Res. 2006 Oct 10;609(1):102-15. doi: 10.1016/j.mrgentox.2006.06.026. Epub 2006 Aug 17. Mutat Res. 2006. PMID: 16916616

3

Two structurally distinct inhibitors of glycogen synthase kinase 3 induced centromere positive micronuclei in human lymphoblastoid TK6 cells.

Mishima M, Tanaka K, Takeiri A, Harada A, Kubo C, Sone S, Nishimura Y, Tachibana Y, Okazaki M. Mishima M, et al. Among authors: harada a. Mutat Res. 2008 Aug 25;643(1-2):29-35. doi: 10.1016/j.mrfmmm.2008.06.001. Epub 2008 Jun 12. Mutat Res. 2008. PMID: 18598706

4

Whole cell-ELISA to measure the gammaH2AX response of six aneugens and eight DNA-damaging chemicals.

Matsuzaki K, Harada A, Takeiri A, Tanaka K, Mishima M. Matsuzaki K, et al. Among authors: harada a. Mutat Res. 2010 Jul 19;700(1-2):71-9. doi: 10.1016/j.mrgentox.2010.05.009. Epub 2010 May 24. Mutat Res. 2010. PMID: 20580854

5

Fluorescent dye-based simple staining for in vivo micronucleus test with flow cytometer.

Harada A, Matsuzaki K, Takeiri A, Tanaka K, Mishima M. Harada A, et al. Mutat Res. 2013 Mar 18;751(2):85-90. doi: 10.1016/j.mrgentox.2012.12.006. Epub 2013 Jan 3. Mutat Res. 2013. PMID: 23291344

6

New DNA probes to detect aneugenicity in rat bone marrow micronucleated cells by a pan-centromeric FISH analysis.

Takeiri A, Motoyama S, Matsuzaki K, Harada A, Taketo J, Katoh C, Tanaka K, Mishima M. Takeiri A, et al. Among authors: harada a. Mutat Res. 2013 Jul 4;755(1):73-80. doi: 10.1016/j.mrgentox.2013.05.011. Epub 2013 May 29. Mutat Res. 2013. PMID: 23726961

7

The predominant role of apoptosis in γH2AX formation induced by aneugens is useful for distinguishing aneugens from clastogens.

Harada A, Matsuzaki K, Takeiri A, Mishima M. Harada A, et al. Mutat Res Genet Toxicol Environ Mutagen. 2014 Sep 1;771:23-9. doi: 10.1016/j.mrgentox.2014.05.010. Epub 2014 Jun 22. Mutat Res Genet Toxicol Environ Mutagen. 2014. PMID: 25308438

8

HSP90 inhibitor CH5164840 induces micronuclei in TK6 cells via an aneugenic mechanism.

Matsuzaki K, Harada A, Tanaka K, Takeiri A, Mishima M. Matsuzaki K, et al. Among authors: harada a. Mutat Res Genet Toxicol Environ Mutagen. 2014 Oct;773:9-13. doi: 10.1016/j.mrgentox.2014.08.002. Epub 2014 Aug 20. Mutat Res Genet Toxicol Environ Mutagen. 2014. PMID: 25308700

9

Giemsa-stained pseudo-micronuclei in rat skin treated with vitamin D₃ analog, pefcalcitol.

Takeiri A, Tanaka K, Harada A, Matsuzaki K, Yano M, Motoyama S, Katoh C, Mishima M. Takeiri A, et al. Among authors: harada a. Genes Environ. 2017 Jun 1;39:17. doi: 10.1186/s41021-017-0077-9. eCollection 2017. Genes Environ. 2017. PMID: 28580039 Free PMC article.

10

Advantages of evaluating γH2AX induction in non-clinical drug development.

Motoyama S, Takeiri A, Tanaka K, Harada A, Matsuzaki K, Taketo J, Matsuo S, Fujii E, Mishima M. Motoyama S, et al. Among authors: harada a. Genes Environ. 2018 May 14;40:10. doi: 10.1186/s41021-018-0098-z. eCollection 2018. Genes Environ. 2018. PMID: 29785231 Free PMC article. Review.

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