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Dexamethasone rapidly suppresses IL-33-stimulated mast cell function by blocking transcription factor activity.
Paranjape A, Chernushevich O, Qayum AA, Spence AJ, Taruselli MT, Abebayehu D, Barnstein BO, McLeod JJ, Baker B, Bajaj GS, Chumanevich AP, Oskeritzian CA, Ryan JJ. Paranjape A, et al. Among authors: oskeritzian ca. J Leukoc Biol. 2016 Dec;100(6):1395-1404. doi: 10.1189/jlb.3A0316-125R. Epub 2016 Jul 21. J Leukoc Biol. 2016. PMID: 27443878 Free PMC article.
Mast cell homeostasis: a fundamental aspect of allergic disease.
Ryan JJ, Kashyap M, Bailey D, Kennedy S, Speiran K, Brenzovich J, Barnstein B, Oskeritzian C, Gomez G. Ryan JJ, et al. Crit Rev Immunol. 2007;27(1):15-32. doi: 10.1615/critrevimmunol.v27.i1.20. Crit Rev Immunol. 2007. PMID: 17430094 Review.
IL-4 and TGF-beta 1 counterbalance one another while regulating mast cell homeostasis.
Macey MR, Sturgill JL, Morales JK, Falanga YT, Morales J, Norton SK, Yerram N, Shim H, Fernando J, Gifillan AM, Gomez G, Schwartz L, Oskeritzian C, Spiegel S, Conrad D, Ryan JJ. Macey MR, et al. J Immunol. 2010 May 1;184(9):4688-95. doi: 10.4049/jimmunol.0903477. Epub 2010 Mar 19. J Immunol. 2010. PMID: 20304823 Free PMC article.
Lyn but not Fyn kinase controls IgG-mediated systemic anaphylaxis.
Falanga YT, Chaimowitz NS, Charles N, Finkelman FD, Pullen NA, Barbour S, Dholaria K, Faber T, Kolawole M, Huang B, Odom S, Rivera J, Carlyon J, Conrad DH, Spiegel S, Oskeritzian CA, Ryan JJ. Falanga YT, et al. Among authors: oskeritzian ca. J Immunol. 2012 May 1;188(9):4360-8. doi: 10.4049/jimmunol.1003223. Epub 2012 Mar 26. J Immunol. 2012. PMID: 22450804 Free PMC article.
A specific sphingosine kinase 1 inhibitor attenuates airway hyperresponsiveness and inflammation in a mast cell-dependent murine model of allergic asthma.
Price MM, Oskeritzian CA, Falanga YT, Harikumar KB, Allegood JC, Alvarez SE, Conrad D, Ryan JJ, Milstien S, Spiegel S. Price MM, et al. Among authors: oskeritzian ca. J Allergy Clin Immunol. 2013 Feb;131(2):501-11.e1. doi: 10.1016/j.jaci.2012.07.014. Epub 2012 Aug 30. J Allergy Clin Immunol. 2013. PMID: 22939756 Free PMC article.
60 results