Zhang Z - Search Results

1

A Small Molecule That Protects the Integrity of the Electron Transfer Chain Blocks the Mitochondrial Apoptotic Pathway.

Jiang X, Li L, Ying Z, Pan C, Huang S, Li L, Dai M, Yan B, Li M, Jiang H, Chen S, Zhang Z, Wang X. Jiang X, et al. Among authors: zhang z. Mol Cell. 2016 Jul 21;63(2):229-239. doi: 10.1016/j.molcel.2016.06.016. Mol Cell. 2016. PMID: 27447985 Free article.

2

A small molecule protects mitochondrial integrity by inhibiting mTOR activity.

Cao R, Li L, Ying Z, Cao Z, Ma Y, Mao X, Li J, Qi X, Zhang Z, Wang X. Cao R, et al. Among authors: zhang z. Proc Natl Acad Sci U S A. 2019 Nov 12;116(46):23332-23338. doi: 10.1073/pnas.1911246116. Epub 2019 Oct 25. Proc Natl Acad Sci U S A. 2019. PMID: 31653761 Free PMC article.

3

Discovery of a new class of highly potent necroptosis inhibitors targeting the mixed lineage kinase domain-like protein.

Yan B, Liu L, Huang S, Ren Y, Wang H, Yao Z, Li L, Chen S, Wang X, Zhang Z. Yan B, et al. Among authors: zhang z. Chem Commun (Camb). 2017 Mar 28;53(26):3637-3640. doi: 10.1039/c7cc00667e. Chem Commun (Camb). 2017. PMID: 28267172

4

Membrane Damage during Ferroptosis Is Caused by Oxidation of Phospholipids Catalyzed by the Oxidoreductases POR and CYB5R1.

Yan B, Ai Y, Sun Q, Ma Y, Cao Y, Wang J, Zhang Z, Wang X. Yan B, et al. Among authors: zhang z. Mol Cell. 2021 Jan 21;81(2):355-369.e10. doi: 10.1016/j.molcel.2020.11.024. Epub 2020 Dec 14. Mol Cell. 2021. PMID: 33321093 Free article.

5

Discovery of Highly Potent 2-Sulfonyl-Pyrimidinyl Derivatives for Apoptosis Inhibition and Ischemia Treatment.

Li L, Jiang X, Huang S, Ying Z, Zhang Z, Pan C, Li S, Wang X, Zhang Z. Li L, et al. Among authors: zhang z. ACS Med Chem Lett. 2017 Mar 1;8(4):407-412. doi: 10.1021/acsmedchemlett.6b00489. eCollection 2017 Apr 13. ACS Med Chem Lett. 2017. PMID: 28435527 Free PMC article.

6

Development and Applications of the Copper-Catalyzed Azide-Alkyne Cycloaddition (CuAAC) as a Bioorthogonal Reaction.

Li L, Zhang Z. Li L, et al. Among authors: zhang z. Molecules. 2016 Oct 24;21(10):1393. doi: 10.3390/molecules21101393. Molecules. 2016. PMID: 27783053 Free PMC article. Review.

7

Discovery of a New Class of Uracil Derivatives as Potential Mixed Lineage Kinase Domain-like Protein (MLKL) Inhibitors.

Cui B, Yan B, Wang K, Li L, Chen S, Zhang Z. Cui B, et al. Among authors: zhang z. J Med Chem. 2022 Oct 13;65(19):12747-12780. doi: 10.1021/acs.jmedchem.2c00548. Epub 2022 Sep 22. J Med Chem. 2022. PMID: 36136378

8

RIP1 kinase inhibitor halts the progression of an immune-induced demyelination disease at the stage of monocyte elevation.

Zhang S, Su Y, Ying Z, Guo D, Pan C, Guo J, Zou Z, Wang L, Zhang Z, Jiang Z, Zhang Z, Wang X. Zhang S, et al. Among authors: zhang z. Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5675-5680. doi: 10.1073/pnas.1819917116. Epub 2019 Mar 5. Proc Natl Acad Sci U S A. 2019. PMID: 30837313 Free PMC article.

9

Activity-based protein profiling reveals GSTO1 as the covalent target of piperlongumine and a promising target for combination therapy for cancer.

Li L , Zhao Y , Cao R , Li L , Cai G , Li J , Qi X , Chen S , Zhang Z . Li L , et al. Among authors: zhang z. Chem Commun (Camb). 2019 Apr 9;55(30):4407-4410. doi: 10.1039/c9cc00917e. Chem Commun (Camb). 2019. PMID: 30916079

10

Assessing POR and CYB5R1 oxidoreductase-mediated oxidative rupture of PUFA in liposomes.

Yan B, Ai Y, Zhang Z, Wang X. Yan B, et al. Among authors: zhang z. STAR Protoc. 2021 Mar 2;2(1):100360. doi: 10.1016/j.xpro.2021.100360. eCollection 2021 Mar 19. STAR Protoc. 2021. PMID: 33718888 Free PMC article.

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