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Chemical Inhibition of Human Thymidylate Kinase and Structural Insights into the Phosphate Binding Loop and Ligand-Induced Degradation.
Chen YH, Hsu HY, Yeh MT, Chen CC, Huang CY, Chung YH, Chang ZF, Kuo WC, Chan NL, Weng JH, Chung BC, Chen YJ, Jian CB, Shen CC, Tai HC, Sheu SY, Fang JM. Chen YH, et al. Among authors: chang zf. J Med Chem. 2016 Nov 10;59(21):9906-9918. doi: 10.1021/acs.jmedchem.6b01280. Epub 2016 Oct 28. J Med Chem. 2016. PMID: 27748121
Two separate functions of NME3 critical for cell survival underlie a neurodegenerative disorder.
Chen CW, Wang HL, Huang CW, Huang CY, Lim WK, Tu IC, Koorapati A, Hsieh ST, Kan HW, Tzeng SR, Liao JC, Chong WM, Naroditzky I, Kidron D, Eran A, Nijim Y, Sela E, Feldman HB, Kalfon L, Raveh-Barak H, Falik-Zaccai TC, Elpeleg O, Mandel H, Chang ZF. Chen CW, et al. Among authors: chang zf. Proc Natl Acad Sci U S A. 2019 Jan 8;116(2):566-574. doi: 10.1073/pnas.1818629116. Epub 2018 Dec 26. Proc Natl Acad Sci U S A. 2019. PMID: 30587587 Free PMC article.
111 results