Hai Y - Search Results

1

Histone deacetylase 6 structure and molecular basis of catalysis and inhibition.

Hai Y, Christianson DW. Hai Y, et al. Nat Chem Biol. 2016 Sep;12(9):741-7. doi: 10.1038/nchembio.2134. Epub 2016 Jul 25. Nat Chem Biol. 2016. PMID: 27454933 Free PMC article.

2

Structure and function of non-native metal clusters in human arginase I.

D'Antonio EL, Hai Y, Christianson DW. D'Antonio EL, et al. Among authors: hai y. Biochemistry. 2012 Oct 23;51(42):8399-409. doi: 10.1021/bi301145n. Epub 2012 Oct 12. Biochemistry. 2012. PMID: 23061982 Free PMC article.

3

Crystal structure of arginase from Leishmania mexicana and implications for the inhibition of polyamine biosynthesis in parasitic infections.

D'Antonio EL, Ullman B, Roberts SC, Dixit UG, Wilson ME, Hai Y, Christianson DW. D'Antonio EL, et al. Among authors: hai y. Arch Biochem Biophys. 2013 Jul 15;535(2):163-76. doi: 10.1016/j.abb.2013.03.015. Epub 2013 Apr 9. Arch Biochem Biophys. 2013. PMID: 23583962 Free PMC article.

4

Formiminoglutamase from Trypanosoma cruzi is an arginase-like manganese metalloenzyme.

Hai Y, Dugery RJ, Healy D, Christianson DW. Hai Y, et al. Biochemistry. 2013 Dec 23;52(51):9294-309. doi: 10.1021/bi401352h. Epub 2013 Nov 21. Biochemistry. 2013. PMID: 24261485 Free PMC article.

5

Crystal structure of Schistosoma mansoni arginase, a potential drug target for the treatment of schistosomiasis.

Hai Y, Edwards JE, Van Zandt MC, Hoffmann KF, Christianson DW. Hai Y, et al. Biochemistry. 2014 Jul 22;53(28):4671-84. doi: 10.1021/bi5004519. Epub 2014 Jul 9. Biochemistry. 2014. PMID: 25007099 Free PMC article.

6

Crystal structure of an arginase-like protein from Trypanosoma brucei that evolved without a binuclear manganese cluster.

Hai Y, Kerkhoven EJ, Barrett MP, Christianson DW. Hai Y, et al. Biochemistry. 2015 Jan 20;54(2):458-71. doi: 10.1021/bi501366a. Epub 2014 Dec 23. Biochemistry. 2015. PMID: 25536859 Free PMC article.

7

Crystal structures of Leishmania mexicana arginase complexed with α,α-disubstituted boronic amino-acid inhibitors.

Hai Y, Christianson DW. Hai Y, et al. Acta Crystallogr F Struct Biol Commun. 2016 Apr;72(Pt 4):300-6. doi: 10.1107/S2053230X16003630. Epub 2016 Mar 16. Acta Crystallogr F Struct Biol Commun. 2016. PMID: 27050264 Free PMC article.

8

Histone deacetylase 10 structure and molecular function as a polyamine deacetylase.

Hai Y, Shinsky SA, Porter NJ, Christianson DW. Hai Y, et al. Nat Commun. 2017 May 18;8:15368. doi: 10.1038/ncomms15368. Nat Commun. 2017. PMID: 28516954 Free PMC article.

9

ARID1A-mutated ovarian cancers depend on HDAC6 activity.

Bitler BG, Wu S, Park PH, Hai Y, Aird KM, Wang Y, Zhai Y, Kossenkov AV, Vara-Ailor A, Rauscher FJ III, Zou W, Speicher DW, Huntsman DG, Conejo-Garcia JR, Cho KR, Christianson DW, Zhang R. Bitler BG, et al. Among authors: hai y. Nat Cell Biol. 2017 Aug;19(8):962-973. doi: 10.1038/ncb3582. Epub 2017 Jul 24. Nat Cell Biol. 2017. PMID: 28737768 Free PMC article.

10

Structural Basis for Aza-Glycine Stabilization of Collagen.

Kasznel AJ, Zhang Y, Hai Y, Chenoweth DM. Kasznel AJ, et al. Among authors: hai y. J Am Chem Soc. 2017 Jul 19;139(28):9427-9430. doi: 10.1021/jacs.7b03398. Epub 2017 Jul 6. J Am Chem Soc. 2017. PMID: 28650147

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