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A small molecule inhibitor of mutant IDH2 rescues cardiomyopathy in a D-2-hydroxyglutaric aciduria type II mouse model.
Wang F, Travins J, Lin Z, Si Y, Chen Y, Powe J, Murray S, Zhu D, Artin E, Gross S, Santiago S, Steadman M, Kernytsky A, Straley K, Lu C, Pop A, Struys EA, Jansen EE, Salomons GS, David MD, Quivoron C, Penard-Lacronique V, Regan KS, Liu W, Dang L, Yang H, Silverman L, Agresta S, Dorsch M, Biller S, Yen K, Cang Y, Su SM, Jin S. Wang F, et al. Among authors: lu c. J Inherit Metab Dis. 2016 Nov;39(6):807-820. doi: 10.1007/s10545-016-9960-y. Epub 2016 Jul 28. J Inherit Metab Dis. 2016. PMID: 27469509 Free PMC article.
A mouse model of a human congenital disorder of glycosylation caused by loss of PMM2.
Chan B, Clasquin M, Smolen GA, Histen G, Powe J, Chen Y, Lin Z, Lu C, Liu Y, Cang Y, Yan Z, Xia Y, Thompson R, Singleton C, Dorsch M, Silverman L, Su SM, Freeze HH, Jin S. Chan B, et al. Among authors: lu c. Hum Mol Genet. 2016 Jun 1;25(11):2182-2193. doi: 10.1093/hmg/ddw085. Epub 2016 Apr 5. Hum Mol Genet. 2016. PMID: 27053713 Free PMC article.
GrB-Fc-KS49, an anti-EMP2 granzyme B fusion protein therapeutic alters immune cell infiltration and suppresses breast cancer growth.
Mohamedali KA, Aguirre B, Lu CH, Chandla A, Kejriwal N, Liu L, Chan AM, Cheung LH, Kok S, Duarte S, Alvarez de Cienfuegos A, Casero D, Rosenblum MG, Wadehra M. Mohamedali KA, et al. Among authors: lu ch. J Immunother Cancer. 2024 Dec 22;12(12):e008891. doi: 10.1136/jitc-2024-008891. J Immunother Cancer. 2024. PMID: 39794935
Recommendation for the use of respiratory syncytial virus vaccines.
Lee PI, Huang YC, Liu CC, Chen SU, Hsueh PR, Ku SC, Chen PY, Chen CJ, Lin YT, Lu CY, Chiu NC, Chi H, Chen YC, Chang FY, Yen MY, Lu CT, Yang KY, Chiu CH, Hwang KP, Lee WS, Yen TY, Hsu JF, Lin YC, Hu YL, Lin TY. Lee PI, et al. Among authors: lu cy, lu ct. J Microbiol Immunol Infect. 2025 Jan 3:S1684-1182(25)00002-7. doi: 10.1016/j.jmii.2024.12.010. Online ahead of print. J Microbiol Immunol Infect. 2025. PMID: 39794196 Review.
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