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Collagen binding properties of the membrane type-1 matrix metalloproteinase (MT1-MMP) hemopexin C domain. The ectodomain of the 44-kDa autocatalytic product of MT1-MMP inhibits cell invasion by disrupting native type I collagen cleavage.
Tam EM, Wu YI, Butler GS, Stack MS, Overall CM. Tam EM, et al. Among authors: overall cm. J Biol Chem. 2002 Oct 11;277(41):39005-14. doi: 10.1074/jbc.M206874200. Epub 2002 Jul 26. J Biol Chem. 2002. PMID: 12145314 Free article.
Utilization of a novel recombinant myoglobin fusion protein expression system to characterize the tissue inhibitor of metalloproteinase (TIMP)-4 and TIMP-2 C-terminal domain and tails by mutagenesis. The importance of acidic residues in binding the MMP-2 hemopexin C-domain.
Kai HS, Butler GS, Morrison CJ, King AE, Pelman GR, Overall CM. Kai HS, et al. Among authors: overall cm. J Biol Chem. 2002 Dec 13;277(50):48696-707. doi: 10.1074/jbc.M209177200. Epub 2002 Oct 8. J Biol Chem. 2002. PMID: 12374789 Free article.
Characterization of the distinct collagen binding, helicase and cleavage mechanisms of matrix metalloproteinase 2 and 14 (gelatinase A and MT1-MMP): the differential roles of the MMP hemopexin c domains and the MMP-2 fibronectin type II modules in collagen triple helicase activities.
Tam EM, Moore TR, Butler GS, Overall CM. Tam EM, et al. Among authors: overall cm. J Biol Chem. 2004 Oct 8;279(41):43336-44. doi: 10.1074/jbc.M407186200. Epub 2004 Aug 2. J Biol Chem. 2004. PMID: 15292230 Free article.
Dissecting the role of matrix metalloproteinases (MMP) and integrin alpha(v)beta3 in angiogenesis in vitro: absence of hemopexin C domain bioactivity, but membrane-Type 1-MMP and alpha(v)beta3 are critical.
Nisato RE, Hosseini G, Sirrenberg C, Butler GS, Crabbe T, Docherty AJ, Wiesner M, Murphy G, Overall CM, Goodman SL, Pepper MS. Nisato RE, et al. Among authors: overall cm. Cancer Res. 2005 Oct 15;65(20):9377-87. doi: 10.1158/0008-5472.CAN-05-1512. Cancer Res. 2005. PMID: 16230401
295 results