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Blockade of interleukin-27 signaling reduces GVHD in mice by augmenting Treg reconstitution and stabilizing Foxp3 expression.
Belle L, Agle K, Zhou V, Yin-Yuan C, Komorowski R, Eastwood D, Logan B, Sun J, Ghilardi N, Cua D, Williams CB, Gaignage M, Marillier R, van Snick J, Drobyski WR. Belle L, et al. Among authors: ghilardi n. Blood. 2016 Oct 20;128(16):2068-2082. doi: 10.1182/blood-2016-02-698241. Epub 2016 Aug 3. Blood. 2016. PMID: 27488350 Free PMC article.
The biology and therapeutic potential of interleukin 27.
Batten M, Ghilardi N. Batten M, et al. Among authors: ghilardi n. J Mol Med (Berl). 2007 Jul;85(7):661-72. doi: 10.1007/s00109-007-0164-7. Epub 2007 Feb 10. J Mol Med (Berl). 2007. PMID: 17294231 Review.
The role of IL-22 in intestinal health and disease.
Keir M, Yi Y, Lu T, Ghilardi N. Keir M, et al. Among authors: ghilardi n. J Exp Med. 2020 Feb 13;217(3):e20192195. doi: 10.1084/jem.20192195. Print 2020 Mar 2. J Exp Med. 2020. PMID: 32997932 Free PMC article. Review.
IL-27 promotes T cell-dependent colitis through multiple mechanisms.
Cox JH, Kljavin NM, Ramamoorthi N, Diehl L, Batten M, Ghilardi N. Cox JH, et al. Among authors: ghilardi n. J Exp Med. 2011 Jan 17;208(1):115-23. doi: 10.1084/jem.20100410. Epub 2010 Dec 20. J Exp Med. 2011. PMID: 21173106 Free PMC article.
A restricted role for TYK2 catalytic activity in human cytokine responses revealed by novel TYK2-selective inhibitors.
Sohn SJ, Barrett K, Van Abbema A, Chang C, Kohli PB, Kanda H, Smith J, Lai Y, Zhou A, Zhang B, Yang W, Williams K, Macleod C, Hurley CA, Kulagowski JJ, Lewin-Koh N, Dengler HS, Johnson AR, Ghilardi N, Zak M, Liang J, Blair WS, Magnuson S, Wu LC. Sohn SJ, et al. Among authors: ghilardi n. J Immunol. 2013 Sep 1;191(5):2205-16. doi: 10.4049/jimmunol.1202859. Epub 2013 Jul 26. J Immunol. 2013. PMID: 23894201 Free PMC article.
71 results