Ploegh HL - Search Results

1

Structures of TorsinA and its disease-mutant complexed with an activator reveal the molecular basis for primary dystonia.

Demircioglu FE, Sosa BA, Ingram J, Ploegh HL, Schwartz TU. Demircioglu FE, et al. Among authors: ploegh hl. Elife. 2016 Aug 4;5:e17983. doi: 10.7554/eLife.17983. Elife. 2016. PMID: 27490483 Free PMC article.

2

A structural element within the HUWE1 HECT domain modulates self-ubiquitination and substrate ubiquitination activities.

Pandya RK, Partridge JR, Love KR, Schwartz TU, Ploegh HL. Pandya RK, et al. Among authors: ploegh hl. J Biol Chem. 2010 Feb 19;285(8):5664-73. doi: 10.1074/jbc.M109.051805. Epub 2009 Dec 10. J Biol Chem. 2010. PMID: 20007713 Free PMC article.

3

Antigen-specific B-cell receptor sensitizes B cells to infection by influenza virus.

Dougan SK, Ashour J, Karssemeijer RA, Popp MW, Avalos AM, Barisa M, Altenburg AF, Ingram JR, Cragnolini JJ, Guo C, Alt FW, Jaenisch R, Ploegh HL. Dougan SK, et al. Among authors: ploegh hl. Nature. 2013 Nov 21;503(7476):406-9. doi: 10.1038/nature12637. Epub 2013 Oct 20. Nature. 2013. PMID: 24141948 Free PMC article.

4

How lamina-associated polypeptide 1 (LAP1) activates Torsin.

Sosa BA, Demircioglu FE, Chen JZ, Ingram J, Ploegh HL, Schwartz TU. Sosa BA, et al. Among authors: ploegh hl. Elife. 2014 Aug 22;3:e03239. doi: 10.7554/eLife.03239. Elife. 2014. PMID: 25149450 Free PMC article.

5

One-step enzymatic modification of the cell surface redirects cellular cytotoxicity and parasite tropism.

Swee LK, Lourido S, Bell GW, Ingram JR, Ploegh HL. Swee LK, et al. Among authors: ploegh hl. ACS Chem Biol. 2015 Feb 20;10(2):460-5. doi: 10.1021/cb500462t. Epub 2014 Nov 10. ACS Chem Biol. 2015. PMID: 25360987 Free PMC article.

6

Intracellular expression of camelid single-domain antibodies specific for influenza virus nucleoprotein uncovers distinct features of its nuclear localization.

Ashour J, Schmidt FI, Hanke L, Cragnolini J, Cavallari M, Altenburg A, Brewer R, Ingram J, Shoemaker C, Ploegh HL. Ashour J, et al. Among authors: ploegh hl. J Virol. 2015 Mar;89(5):2792-800. doi: 10.1128/JVI.02693-14. Epub 2014 Dec 24. J Virol. 2015. PMID: 25540369 Free PMC article.

7

HypE-specific nanobodies as tools to modulate HypE-mediated target AMPylation.

Truttmann MC, Wu Q, Stiegeler S, Duarte JN, Ingram J, Ploegh HL. Truttmann MC, et al. Among authors: ploegh hl. J Biol Chem. 2015 Apr 3;290(14):9087-100. doi: 10.1074/jbc.M114.634287. Epub 2015 Feb 12. J Biol Chem. 2015. PMID: 25678711 Free PMC article.

8

Site-specific protein modification using immobilized sortase in batch and continuous-flow systems.

Witte MD, Wu T, Guimaraes CP, Theile CS, Blom AE, Ingram JR, Li Z, Kundrat L, Goldberg SD, Ploegh HL. Witte MD, et al. Among authors: ploegh hl. Nat Protoc. 2015 Mar;10(3):508-16. doi: 10.1038/nprot.2015.026. Epub 2015 Feb 26. Nat Protoc. 2015. PMID: 25719269 Free PMC article.

9

Structural biology. Structural basis for chemokine recognition and activation of a viral G protein-coupled receptor.

Burg JS, Ingram JR, Venkatakrishnan AJ, Jude KM, Dukkipati A, Feinberg EN, Angelini A, Waghray D, Dror RO, Ploegh HL, Garcia KC. Burg JS, et al. Among authors: ploegh hl. Science. 2015 Mar 6;347(6226):1113-7. doi: 10.1126/science.aaa5026. Science. 2015. PMID: 25745166 Free PMC article.

10

Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining.

Maruyama T, Dougan SK, Truttmann MC, Bilate AM, Ingram JR, Ploegh HL. Maruyama T, et al. Among authors: ploegh hl. Nat Biotechnol. 2015 May;33(5):538-42. doi: 10.1038/nbt.3190. Epub 2015 Mar 23. Nat Biotechnol. 2015. PMID: 25798939 Free PMC article.

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