Doucet N - Search Results

1

Conformational Sub-states and Populations in Enzyme Catalysis.

Agarwal PK, Doucet N, Chennubhotla C, Ramanathan A, Narayanan C. Agarwal PK, et al. Among authors: doucet n. Methods Enzymol. 2016;578:273-97. doi: 10.1016/bs.mie.2016.05.023. Epub 2016 Jul 9. Methods Enzymol. 2016. PMID: 27497171 Free PMC article. Review.

2

Can enzyme engineering benefit from the modulation of protein motions? Lessons learned from NMR relaxation dispersion experiments.

Doucet N. Doucet N. Protein Pept Lett. 2011 Apr;18(4):336-43. doi: 10.2174/092986611794653950. Protein Pept Lett. 2011. PMID: 21222641 Review.

3

Conservation of flexible residue clusters among structural and functional enzyme homologues.

Gagné D, Charest LA, Morin S, Kovrigin EL, Doucet N. Gagné D, et al. Among authors: doucet n. J Biol Chem. 2012 Dec 28;287(53):44289-300. doi: 10.1074/jbc.M112.394866. Epub 2012 Nov 7. J Biol Chem. 2012. PMID: 23135272 Free PMC article.

4

Structural and functional importance of local and global conformational fluctuations in the RNase A superfamily.

Gagné D, Doucet N. Gagné D, et al. Among authors: doucet n. FEBS J. 2013 Nov;280(22):5596-607. doi: 10.1111/febs.12371. Epub 2013 Jun 24. FEBS J. 2013. PMID: 23763751 Free article. Review.

5

Sequence-specific backbone (1)H, (13)C, and (15)N resonance assignments of human ribonuclease 4.

Gagné D, Doucet N. Gagné D, et al. Among authors: doucet n. Biomol NMR Assign. 2015 Apr;9(1):181-5. doi: 10.1007/s12104-014-9570-2. Epub 2014 Jul 17. Biomol NMR Assign. 2015. PMID: 25030111 Free PMC article.

6

Network of long-range concerted chemical shift displacements upon ligand binding to human angiogenin.

Gagné D, Narayanan C, Doucet N. Gagné D, et al. Among authors: doucet n. Protein Sci. 2015 Apr;24(4):525-33. doi: 10.1002/pro.2613. Epub 2014 Dec 26. Protein Sci. 2015. PMID: 25450558 Free PMC article.

7

Perturbation of the Conformational Dynamics of an Active-Site Loop Alters Enzyme Activity.

Gagné D, French RL, Narayanan C, Simonović M, Agarwal PK, Doucet N. Gagné D, et al. Among authors: doucet n. Structure. 2015 Dec 1;23(12):2256-2266. doi: 10.1016/j.str.2015.10.011. Epub 2015 Nov 19. Structure. 2015. PMID: 26655472 Free PMC article.

8

Ligand Binding Enhances Millisecond Conformational Exchange in Xylanase B2 from Streptomyces lividans.

Gagné D, Narayanan C, Nguyen-Thi N, Roux LD, Bernard DN, Brunzelle JS, Couture JF, Agarwal PK, Doucet N. Gagné D, et al. Among authors: doucet n. Biochemistry. 2016 Aug 2;55(30):4184-96. doi: 10.1021/acs.biochem.6b00130. Epub 2016 Jul 21. Biochemistry. 2016. PMID: 27387012 Free PMC article.

9

Sequence-specific backbone resonance assignments and microsecond timescale molecular dynamics simulation of human eosinophil-derived neurotoxin.

Gagné D, Narayanan C, Bafna K, Charest LA, Agarwal PK, Doucet N. Gagné D, et al. Among authors: doucet n. Biomol NMR Assign. 2017 Oct;11(2):143-149. doi: 10.1007/s12104-017-9736-9. Epub 2017 Mar 7. Biomol NMR Assign. 2017. PMID: 28271277 Free PMC article.

10

Role of Conformational Motions in Enzyme Function: Selected Methodologies and Case Studies.

Narayanan C, Bernard DN, Doucet N. Narayanan C, et al. Among authors: doucet n. Catalysts. 2016 Jun;6(6):81. doi: 10.3390/catal6060081. Epub 2016 May 27. Catalysts. 2016. PMID: 28367322 Free PMC article.

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