Edgington-Mitchell LE - Search Results

1

Legumain is activated in macrophages during pancreatitis.

Edgington-Mitchell LE, Wartmann T, Fleming AK, Gocheva V, van der Linden WA, Withana NP, Verdoes M, Aurelio L, Edgington-Mitchell D, Lieu T, Parker BS, Graham B, Reinheckel T, Furness JB, Joyce JA, Storz P, Halangk W, Bogyo M, Bunnett NW. Edgington-Mitchell LE, et al. Am J Physiol Gastrointest Liver Physiol. 2016 Sep 1;311(3):G548-60. doi: 10.1152/ajpgi.00047.2016. Epub 2016 Aug 11. Am J Physiol Gastrointest Liver Physiol. 2016. PMID: 27514475 Free PMC article.

2

Probes to monitor activity of the paracaspase MALT1.

Hachmann J, Edgington-Mitchell LE, Poreba M, Sanman LE, Drag M, Bogyo M, Salvesen GS. Hachmann J, et al. Chem Biol. 2015 Jan 22;22(1):139-47. doi: 10.1016/j.chembiol.2014.11.011. Epub 2014 Dec 31. Chem Biol. 2015. PMID: 25556944 Free PMC article.

3

Demonstration of elevated levels of active cathepsin S in dextran sulfate sodium colitis using a new activatable probe.

Barlow N, Nasser Y, Zhao P, Sharma N, Guerrero-Alba R, Edgington-Mitchell LE, Lieu T, Veldhuis NA, Poole DP, Conner JW, Lindström E, Craig AW, Graham B, Vanner SJ, Bunnett NW. Barlow N, et al. Neurogastroenterol Motil. 2015 Nov;27(11):1675-80. doi: 10.1111/nmo.12656. Epub 2015 Aug 24. Neurogastroenterol Motil. 2015. PMID: 26303377

4

Cysteine cathepsin activity suppresses osteoclastogenesis of myeloid-derived suppressor cells in breast cancer.

Edgington-Mitchell LE, Rautela J, Duivenvoorden HM, Jayatilleke KM, van der Linden WA, Verdoes M, Bogyo M, Parker BS. Edgington-Mitchell LE, et al. Oncotarget. 2015 Sep 29;6(29):27008-22. doi: 10.18632/oncotarget.4714. Oncotarget. 2015. PMID: 26308073 Free PMC article.

5

Pathophysiological roles of proteases in gastrointestinal disease.

Edgington-Mitchell LE. Edgington-Mitchell LE. Am J Physiol Gastrointest Liver Physiol. 2016 Feb 15;310(4):G234-9. doi: 10.1152/ajpgi.00393.2015. Epub 2015 Dec 23. Am J Physiol Gastrointest Liver Physiol. 2016. PMID: 26702140 Free article. Review.

6

Detection of Active Caspases During Apoptosis Using Fluorescent Activity-Based Probes.

Edgington-Mitchell LE, Bogyo M. Edgington-Mitchell LE, et al. Methods Mol Biol. 2016;1419:27-39. doi: 10.1007/978-1-4939-3581-9_3. Methods Mol Biol. 2016. PMID: 27108429 Free PMC article.

7

Antagonism of the proinflammatory and pronociceptive actions of canonical and biased agonists of protease-activated receptor-2.

Lieu T, Savage E, Zhao P, Edgington-Mitchell L, Barlow N, Bron R, Poole DP, McLean P, Lohman RJ, Fairlie DP, Bunnett NW. Lieu T, et al. Br J Pharmacol. 2016 Sep;173(18):2752-65. doi: 10.1111/bph.13554. Epub 2016 Aug 3. Br J Pharmacol. 2016. PMID: 27423137 Free PMC article.

8

Long noncoding RNAs: novel links to inflammatory bowel disease?

Edgington-Mitchell LE. Edgington-Mitchell LE. Am J Physiol Gastrointest Liver Physiol. 2016 Sep 1;311(3):G444-5. doi: 10.1152/ajpgi.00271.2016. Epub 2016 Aug 4. Am J Physiol Gastrointest Liver Physiol. 2016. PMID: 27492332 Free article. No abstract available.

9

Live Cell Imaging and Profiling of Cysteine Cathepsin Activity Using a Quenched Activity-Based Probe.

Edgington-Mitchell LE, Bogyo M, Verdoes M. Edgington-Mitchell LE, et al. Methods Mol Biol. 2017;1491:145-159. doi: 10.1007/978-1-4939-6439-0_11. Methods Mol Biol. 2017. PMID: 27778287

10

Fluorescent diphenylphosphonate-based probes for detection of serine protease activity during inflammation.

Edgington-Mitchell LE, Barlow N, Aurelio L, Samha A, Szabo M, Graham B, Bunnett N. Edgington-Mitchell LE, et al. Bioorg Med Chem Lett. 2017 Jan 15;27(2):254-260. doi: 10.1016/j.bmcl.2016.11.064. Epub 2016 Nov 25. Bioorg Med Chem Lett. 2017. PMID: 27923620 Free PMC article.

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