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Mouse social stress induces increased fear conditioning, helplessness and fatigue to physical challenge together with markers of altered immune and dopamine function.
Azzinnari D, Sigrist H, Staehli S, Palme R, Hildebrandt T, Leparc G, Hengerer B, Seifritz E, Pryce CR. Azzinnari D, et al. Among authors: sigrist h. Neuropharmacology. 2014 Oct;85:328-41. doi: 10.1016/j.neuropharm.2014.05.039. Epub 2014 Jun 5. Neuropharmacology. 2014. PMID: 24907589 Free article.
CD40-TNF activation in mice induces extended sickness behavior syndrome co-incident with but not dependent on activation of the kynurenine pathway.
Cathomas F, Fuertig R, Sigrist H, Newman GN, Hoop V, Bizzozzero M, Mueller A, Luippold A, Ceci A, Hengerer B, Seifritz E, Fontana A, Pryce CR. Cathomas F, et al. Among authors: sigrist h. Brain Behav Immun. 2015 Nov;50:125-140. doi: 10.1016/j.bbi.2015.06.184. Epub 2015 Jul 11. Brain Behav Immun. 2015. PMID: 26173174
Mouse chronic social stress increases blood and brain kynurenine pathway activity and fear behaviour: Both effects are reversed by inhibition of indoleamine 2,3-dioxygenase.
Fuertig R, Azzinnari D, Bergamini G, Cathomas F, Sigrist H, Seifritz E, Vavassori S, Luippold A, Hengerer B, Ceci A, Pryce CR. Fuertig R, et al. Among authors: sigrist h. Brain Behav Immun. 2016 May;54:59-72. doi: 10.1016/j.bbi.2015.12.020. Epub 2015 Dec 24. Brain Behav Immun. 2016. PMID: 26724575
88 results