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New pyrazole derivative 5-[1-(4-fluorophenyl)-1H-pyrazol-4-yl]-2H-tetrazole: synthesis and assessment of some biological activities.
de Oliveira LP, da Silva DP, Florentino IF, Fajemiroye JO, de Oliveira TS, Marcelino RI, Pazini F, Lião LM, Ghedini PC, de Moura SS, Valadares MC, de Carvalho VV, Vaz BG, Menegatti R, Costa EA. de Oliveira LP, et al. Among authors: valadares mc. Chem Biol Drug Des. 2017 Jan;89(1):124-135. doi: 10.1111/cbdd.12838. Epub 2016 Sep 14. Chem Biol Drug Des. 2017. PMID: 27526659
4-Nerolidylcatechol and its synthetic analogues: antioxidant activity and toxicity evaluation.
Mendanha da Cunha CR, Mendanha Neto SA, Carlos da Silva C, Cortez AP, Gomes Mdo N, Martins FI, Alonso A, Rezende KR, Menegatti R, de Magalhães MT, Valadares MC. Mendanha da Cunha CR, et al. Among authors: valadares mc. Eur J Med Chem. 2013 Apr;62:371-8. doi: 10.1016/j.ejmech.2012.12.028. Epub 2012 Dec 20. Eur J Med Chem. 2013. PMID: 23376996
Antinociceptive and Anti-Inflammatory Activities of the Ethanolic Extract from Synadenium umbellatum Pax. (Euphorbiaceae) Leaves and Its Fractions.
Borges R, Nascimento MV, de Carvalho AA, Valadares MC, de Paula JR, Costa EA, da Cunha LC. Borges R, et al. Among authors: valadares mc. Evid Based Complement Alternat Med. 2013;2013:715650. doi: 10.1155/2013/715650. Epub 2013 Jan 21. Evid Based Complement Alternat Med. 2013. PMID: 23401717 Free PMC article.
4-Nerolidylcatechol analogues as promising anticancer agents.
Cortez AP, de Ávila RI, da Cunha CR, Santos AP, Menegatti R, Rezende KR, Valadares MC. Cortez AP, et al. Among authors: valadares mc. Eur J Pharmacol. 2015 Oct 15;765:517-24. doi: 10.1016/j.ejphar.2015.08.024. Epub 2015 Aug 20. Eur J Pharmacol. 2015. PMID: 26297972 Free article.
Involvement of the monoamine system in antidepressant-like properties of 4-(1-phenyl-1h-pyrazol-4-ylmethyl)-piperazine-1-carboxylic acid ethyl ester.
Galdino PM, de Oliveira DR, Florentino IF, Fajemiroye JO, Valadares MC, de Moura SS, da Rocha FF, de Lima TC, Costa EA, Menegatti R. Galdino PM, et al. Among authors: valadares mc. Life Sci. 2015 Dec 15;143:187-93. doi: 10.1016/j.lfs.2015.11.009. Epub 2015 Nov 10. Life Sci. 2015. PMID: 26569034 Free article.
Photoprotective effect and acute oral systemic toxicity evaluation of the novel heterocyclic compound LQFM048.
Vinhal DC, de Ávila RI, Vieira MS, Luzin RM, Quintino MP, Nunes LM, Ribeiro AC, de Camargo HS, Pinto AC, Dos Santos Júnior HM, Chiari BG, Isaac V, Valadares MC, Martins TD, Lião LM, de S Gil E, Menegatti R. Vinhal DC, et al. Among authors: valadares mc. J Photochem Photobiol B. 2016 Aug;161:50-8. doi: 10.1016/j.jphotobiol.2016.03.042. Epub 2016 Apr 2. J Photochem Photobiol B. 2016. PMID: 27208746
Induction of apoptosis in Ehrlich ascites tumour cells via p53 activation by a novel small-molecule MDM2 inhibitor - LQFM030.
da Mota MF, Cortez AP, Benfica PL, Rodrigues Bdos S, Castro TF, Macedo LM, Castro CH, Lião LM, de Carvalho FS, Romeiro LA, Menegatti R, Verli H, Villavicencio B, Valadares MC. da Mota MF, et al. Among authors: valadares mc. J Pharm Pharmacol. 2016 Sep;68(9):1143-59. doi: 10.1111/jphp.12573. Epub 2016 Jun 28. J Pharm Pharmacol. 2016. PMID: 27350017
141 results