LeCluyse E - Search Results

1

Development of an in vitro high content imaging assay for quantitative assessment of CAR-dependent mouse, rat, and human primary hepatocyte proliferation.

Soldatow V, Peffer RC, Trask OJ, Cowie DE, Andersen ME, LeCluyse E, Deisenroth C. Soldatow V, et al. Among authors: lecluyse e. Toxicol In Vitro. 2016 Oct;36:224-237. doi: 10.1016/j.tiv.2016.08.006. Epub 2016 Aug 12. Toxicol In Vitro. 2016. PMID: 27530964

2

A micropatterned hepatocyte coculture model for assessment of liver toxicity using high-content imaging analysis.

Trask OJ Jr, Moore A, LeCluyse EL. Trask OJ Jr, et al. Assay Drug Dev Technol. 2014 Jan-Feb;12(1):16-27. doi: 10.1089/adt.2013.525. Epub 2014 Jan 20. Assay Drug Dev Technol. 2014. PMID: 24444127

3

Identifying qualitative differences in PPARα signaling networks in human and rat hepatocytes and their significance for next generation chemical risk assessment methods.

McMullen PD, Bhattacharya S, Woods CG, Pendse SN, McBride MT, Soldatow VY, Deisenroth C, LeCluyse EL, Clewell RA, Andersen ME. McMullen PD, et al. Among authors: lecluyse el. Toxicol In Vitro. 2020 Apr;64:104463. doi: 10.1016/j.tiv.2019.02.017. Epub 2019 Oct 15. Toxicol In Vitro. 2020. PMID: 31628012 Free article.

4

Organotypic liver culture models: meeting current challenges in toxicity testing.

LeCluyse EL, Witek RP, Andersen ME, Powers MJ. LeCluyse EL, et al. Crit Rev Toxicol. 2012 Jul;42(6):501-48. doi: 10.3109/10408444.2012.682115. Epub 2012 May 15. Crit Rev Toxicol. 2012. PMID: 22582993 Free PMC article. Review.

5

Development of 3D dynamic flow model of human liver and its application to prediction of metabolic clearance of 7-ethoxycoumarin.

Choi K, Pfund WP, Andersen ME, Thomas RS, Clewell HJ, LeCluyse EL. Choi K, et al. Among authors: lecluyse el. Tissue Eng Part C Methods. 2014 Aug;20(8):641-51. doi: 10.1089/ten.TEC.2013.0562. Epub 2014 Mar 4. Tissue Eng Part C Methods. 2014. PMID: 24294911

6

Dose-response in a high density three-dimensional liver device with real-time bioenergetic and metabolic flux quantification.

Tikunov AP, Shim YS, Bhattarai N, Siler SQ, Soldatow V, LeCluyse EL, McDunn JE, Watkins PB, Macdonald JM. Tikunov AP, et al. Among authors: lecluyse el. Toxicol In Vitro. 2017 Dec;45(Pt 1):119-127. doi: 10.1016/j.tiv.2017.08.021. Epub 2017 Sep 1. Toxicol In Vitro. 2017. PMID: 28867505

7

Long-Term Engineered Cultures of Primary Mouse Hepatocytes for Strain and Species Comparison Studies During Drug Development.

Ware BR, Brown GE, Soldatow VY, LeCluyse EL, Khetani SR. Ware BR, et al. Among authors: lecluyse el. Gene Expr. 2019 Nov 4;19(3):199-214. doi: 10.3727/105221619X15638857793317. Epub 2019 Jul 24. Gene Expr. 2019. PMID: 31340881 Free PMC article.

8

Development of an In Vitro Human Thyroid Microtissue Model for Chemical Screening.

Deisenroth C, Soldatow VY, Ford J, Stewart W, Brinkman C, LeCluyse EL, MacMillan DK, Thomas RS. Deisenroth C, et al. Toxicol Sci. 2020 Mar 1;174(1):63-78. doi: 10.1093/toxsci/kfz238. Toxicol Sci. 2020. PMID: 31808822 Free PMC article.

9

miR-122 Release in Exosomes Precedes Overt Tolvaptan-Induced Necrosis in a Primary Human Hepatocyte Micropatterned Coculture Model.

Mosedale M, Eaddy JS, Trask OJ Jr, Holman NS, Wolf KK, LeCluyse E, Ware BR, Khetani SR, Lu J, Brock WJ, Roth SE, Watkins PB. Mosedale M, et al. Among authors: lecluyse e. Toxicol Sci. 2018 Jan 1;161(1):149-158. doi: 10.1093/toxsci/kfx206. Toxicol Sci. 2018. PMID: 29029277 Free PMC article.

10

In vitro models for liver toxicity testing.

Soldatow VY, Lecluyse EL, Griffith LG, Rusyn I. Soldatow VY, et al. Toxicol Res (Camb). 2013 Jan 1;2(1):23-39. doi: 10.1039/C2TX20051A. Epub 2012 Nov 23. Toxicol Res (Camb). 2013. PMID: 23495363 Free PMC article.

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