McCarthy NJ - Search Results

1

Increasing the performance of pooled CRISPR-Cas9 drop-out screening.

Cross BC, Lawo S, Archer CR, Hunt JR, Yarker JL, Riccombeni A, Little AS, McCarthy NJ, Moore JD. Cross BC, et al. Among authors: mccarthy nj. Sci Rep. 2016 Aug 22;6:31782. doi: 10.1038/srep31782. Sci Rep. 2016. PMID: 27545104 Free PMC article.

2

Dual direction CRISPR transcriptional regulation screening uncovers gene networks driving drug resistance.

le Sage C, Lawo S, Panicker P, Scales TME, Rahman SA, Little AS, McCarthy NJ, Moore JD, Cross BCS. le Sage C, et al. Among authors: mccarthy nj. Sci Rep. 2017 Dec 18;7(1):17693. doi: 10.1038/s41598-017-18172-6. Sci Rep. 2017. PMID: 29255251 Free PMC article.

3

A Medium-Throughput Single Cell CRISPR-Cas9 Assay to Assess Gene Essentiality.

Grassian AR, Scales TME, Knutson SK, Kuntz KW, McCarthy NJ, Lowe CE, Moore JD, Copeland RA, Keilhack H, Smith JJ, Wickenden JA, Ribich S. Grassian AR, et al. Among authors: mccarthy nj. Biol Proced Online. 2015 Nov 14;17:15. doi: 10.1186/s12575-015-0028-4. eCollection 2015. Biol Proced Online. 2015. PMID: 26578851 Free PMC article.

4

Retroviral insertional mutagenesis implicates E3 ubiquitin ligase RNF168 in the control of cell proliferation and survival.

Kizilors A, Pickard MR, Schulte CE, Yacqub-Usman K, McCarthy NJ, Gan SU, Darling D, Gäken J, Williams GT, Farzaneh F. Kizilors A, et al. Among authors: mccarthy nj. Biosci Rep. 2017 Aug 31;37(4):BSR20170843. doi: 10.1042/BSR20170843. Epub 2017 Jul 27. Biosci Rep. 2017. PMID: 28754805 Free PMC article.

5

Metabonomics study of the effects of single copy mutant KRAS in the presence or absence of WT allele using human HCT116 isogenic cell lines.

Varshavi D, Varshavi D, McCarthy N, Veselkov K, Keun HC, Everett JR. Varshavi D, et al. Metabolomics. 2021 Nov 25;17(12):104. doi: 10.1007/s11306-021-01852-w. Metabolomics. 2021. PMID: 34822010 Free PMC article.

6

Metabolic characterization of colorectal cancer cells harbouring different KRAS mutations in codon 12, 13, 61 and 146 using human SW48 isogenic cell lines.

Varshavi D, Varshavi D, McCarthy N, Veselkov K, Keun HC, Everett JR. Varshavi D, et al. Metabolomics. 2020 Apr 16;16(4):51. doi: 10.1007/s11306-020-01674-2. Metabolomics. 2020. PMID: 32300895 Free PMC article.

7

Tumour suppressors: Turning a negative into a positive.

McCarthy N. McCarthy N. Nat Rev Cancer. 2016 May;16(5):272-3. doi: 10.1038/nrc.2016.39. Epub 2016 Apr 15. Nat Rev Cancer. 2016. PMID: 27079804 No abstract available.

8

Tumour metabolism: RED(D1) or dead.

McCarthy N. McCarthy N. Nat Rev Cancer. 2016 Nov 23;16(12):754-755. doi: 10.1038/nrc.2016.132. Nat Rev Cancer. 2016. PMID: 27876770 No abstract available.

9

Isolation of genes controlling apoptosis through their effects on cell survival.

Williams GT, Hughes JP, Stoneman V, Anderson CL, McCarthy NJ, Mourtada-Maarabouni M, Pickard M, Hedge VL, Trayner I, Farzaneh F. Williams GT, et al. Among authors: mccarthy nj. Gene Ther Mol Biol. 2006 Dec 12;10(B):255-262. Gene Ther Mol Biol. 2006. PMID: 17372619 Free PMC article.

10

The Epstein-Barr virus gene BHRF1, a homologue of the cellular oncogene Bcl-2, inhibits apoptosis induced by gamma radiation and chemotherapeutic drugs.

McCarthy NJ, Hazlewood SA, Huen DS, Rickinson AB, Williams GT. McCarthy NJ, et al. Adv Exp Med Biol. 1996;406:83-97. doi: 10.1007/978-1-4899-0274-0_9. Adv Exp Med Biol. 1996. PMID: 8910674

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