Jmaeff S - Search Results

1

Neurotrophin receptor agonists and antagonists as therapeutic agents: An evolving paradigm.

Josephy-Hernandez S, Jmaeff S, Pirvulescu I, Aboulkassim T, Saragovi HU. Josephy-Hernandez S, et al. Among authors: jmaeff s. Neurobiol Dis. 2017 Jan;97(Pt B):139-155. doi: 10.1016/j.nbd.2016.08.004. Epub 2016 Aug 18. Neurobiol Dis. 2017. PMID: 27546056 Review.

2

p75NTR and Its Ligand ProNGF Activate Paracrine Mechanisms Etiological to the Vascular, Inflammatory, and Neurodegenerative Pathologies of Diabetic Retinopathy.

Barcelona PF, Sitaras N, Galan A, Esquiva G, Jmaeff S, Jian Y, Sarunic MV, Cuenca N, Sapieha P, Saragovi HU. Barcelona PF, et al. Among authors: jmaeff s. J Neurosci. 2016 Aug 24;36(34):8826-41. doi: 10.1523/JNEUROSCI.4278-15.2016. J Neurosci. 2016. PMID: 27559166 Free PMC article.

3

p75^NTR antagonists attenuate photoreceptor cell loss in murine models of retinitis pigmentosa.

Platón-Corchado M, Barcelona PF, Jmaeff S, Marchena M, Hernández-Pinto AM, Hernández-Sánchez C, Saragovi HU, de la Rosa EJ. Platón-Corchado M, et al. Among authors: jmaeff s. Cell Death Dis. 2017 Jul 13;8(7):e2922. doi: 10.1038/cddis.2017.306. Cell Death Dis. 2017. PMID: 28703796 Free PMC article.

4

In retinitis pigmentosa TrkC.T1-dependent vectorial Erk activity upregulates glial TNF-α, causing selective neuronal death.

Galán A, Jmaeff S, Barcelona PF, Brahimi F, Sarunic MV, Saragovi HU. Galán A, et al. Among authors: jmaeff s. Cell Death Dis. 2017 Dec 14;8(12):3222. doi: 10.1038/s41419-017-0074-8. Cell Death Dis. 2017. PMID: 29242588 Free PMC article.

5

Small-molecule agonists of the RET receptor tyrosine kinase activate biased trophic signals that are influenced by the presence of GFRa1 co-receptors.

Jmaeff S, Sidorova Y, Nedev H, Saarma M, Saragovi HU. Jmaeff S, et al. J Biol Chem. 2020 May 8;295(19):6532-6542. doi: 10.1074/jbc.RA119.011802. Epub 2020 Apr 3. J Biol Chem. 2020. PMID: 32245892 Free PMC article.

6

Small-Molecule Ligands that Bind the RET Receptor Activate Neuroprotective Signals Independent of but Modulated by Coreceptor GFRα1.

Jmaeff S, Sidorova Y, Lippiatt H, Barcelona PF, Nedev H, Saragovi LM, Hancock MA, Saarma M, Saragovi HU. Jmaeff S, et al. Mol Pharmacol. 2020 Jul;98(1):1-12. doi: 10.1124/mol.119.118950. Epub 2020 May 3. Mol Pharmacol. 2020. PMID: 32362584

7

Alternative Splicing of a Receptor Intracellular Domain Yields Different Ectodomain Conformations, Enabling Isoform-Selective Functional Ligands.

Brahimi F, Galan A, Jmaeff S, Barcelona PF, De Jay N, Dejgaard K, Young JC, Kleinman CL, Thomas DY, Saragovi HU. Brahimi F, et al. Among authors: jmaeff s. iScience. 2020 Aug 10;23(9):101447. doi: 10.1016/j.isci.2020.101447. eCollection 2020 Sep 25. iScience. 2020. PMID: 32829283 Free PMC article.

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