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Treatment of experimental allergic encephalomyelitis (EAE) by a rationally designed cyclic analogue of myelin basic protein (MBP) epitope 72-85.
Tselios T, Daliani I, Deraos S, Thymianou S, Matsoukas E, Troganis A, Gerothanassis I, Mouzaki A, Mavromoustakos T, Probert L, Matsoukas J. Tselios T, et al. Among authors: matsoukas e, matsoukas j. Bioorg Med Chem Lett. 2000 Dec 18;10(24):2713-7. doi: 10.1016/s0960-894x(00)00556-4. Bioorg Med Chem Lett. 2000. PMID: 11133075
Design and synthesis of a novel potent myelin basic protein epitope 87-99 cyclic analogue: enhanced stability and biological properties of mimics render them a potentially new class of immunomodulators.
Matsoukas J, Apostolopoulos V, Kalbacher H, Papini AM, Tselios T, Chatzantoni K, Biagioli T, Lolli F, Deraos S, Papathanassopoulos P, Troganis A, Mantzourani E, Mavromoustakos T, Mouzaki A. Matsoukas J, et al. J Med Chem. 2005 Mar 10;48(5):1470-80. doi: 10.1021/jm040849g. J Med Chem. 2005. PMID: 15743189
162 results