Yon J - Search Results

1

Structure of the Epigenetic Oncogene MMSET and Inhibition by N-Alkyl Sinefungin Derivatives.

Tisi D, Chiarparin E, Tamanini E, Pathuri P, Coyle JE, Hold A, Holding FP, Amin N, Martin AC, Rich SJ, Berdini V, Yon J, Acklam P, Burke R, Drouin L, Harmer JE, Jeganathan F, van Montfort RL, Newbatt Y, Tortorici M, Westlake M, Wood A, Hoelder S, Heightman TD. Tisi D, et al. Among authors: yon j. ACS Chem Biol. 2016 Nov 18;11(11):3093-3105. doi: 10.1021/acschembio.6b00308. Epub 2016 Sep 27. ACS Chem Biol. 2016. PMID: 27571355

2

Crystal structure of human soluble adenylate cyclase reveals a distinct, highly flexible allosteric bicarbonate binding pocket.

Saalau-Bethell SM, Berdini V, Cleasby A, Congreve M, Coyle JE, Lock V, Murray CW, O'Brien MA, Rich SJ, Sambrook T, Vinkovic M, Yon JR, Jhoti H. Saalau-Bethell SM, et al. Among authors: yon jr. ChemMedChem. 2014 Apr;9(4):823-32. doi: 10.1002/cmdc.201300480. Epub 2014 Feb 24. ChemMedChem. 2014. PMID: 24616449 Free PMC article.

3

Crystal structure of human CDK4 in complex with a D-type cyclin.

Day PJ, Cleasby A, Tickle IJ, O'Reilly M, Coyle JE, Holding FP, McMenamin RL, Yon J, Chopra R, Lengauer C, Jhoti H. Day PJ, et al. Among authors: yon j. Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4166-70. doi: 10.1073/pnas.0809645106. Epub 2009 Feb 23. Proc Natl Acad Sci U S A. 2009. PMID: 19237565 Free PMC article.

4

High-throughput protein crystallography and drug discovery.

Tickle I, Sharff A, Vinkovic M, Yon J, Jhoti H. Tickle I, et al. Among authors: yon j. Chem Soc Rev. 2004 Oct 20;33(8):558-65. doi: 10.1039/b314510g. Epub 2004 Sep 20. Chem Soc Rev. 2004. PMID: 15480479

5

Apo and inhibitor complex structures of BACE (beta-secretase).

Patel S, Vuillard L, Cleasby A, Murray CW, Yon J. Patel S, et al. Among authors: yon j. J Mol Biol. 2004 Oct 15;343(2):407-16. doi: 10.1016/j.jmb.2004.08.018. J Mol Biol. 2004. PMID: 15451669

6

Structure of the BTB domain of Keap1 and its interaction with the triterpenoid antagonist CDDO.

Cleasby A, Yon J, Day PJ, Richardson C, Tickle IJ, Williams PA, Callahan JF, Carr R, Concha N, Kerns JK, Qi H, Sweitzer T, Ward P, Davies TG. Cleasby A, et al. Among authors: yon j. PLoS One. 2014 Jun 4;9(6):e98896. doi: 10.1371/journal.pone.0098896. eCollection 2014. PLoS One. 2014. PMID: 24896564 Free PMC article.

7

Structure of a CBS-domain pair from the regulatory gamma1 subunit of human AMPK in complex with AMP and ZMP.

Day P, Sharff A, Parra L, Cleasby A, Williams M, Hörer S, Nar H, Redemann N, Tickle I, Yon J. Day P, et al. Among authors: yon j. Acta Crystallogr D Biol Crystallogr. 2007 May;63(Pt 5):587-96. doi: 10.1107/S0907444907009110. Epub 2007 Apr 21. Acta Crystallogr D Biol Crystallogr. 2007. PMID: 17452784

8

Recombinant insect cell expression and purification of human beta-secretase (BACE-1) for X-ray crystallography.

Bruinzeel W, Yon J, Giovannelli S, Masure S. Bruinzeel W, et al. Among authors: yon j. Protein Expr Purif. 2002 Oct;26(1):139-48. doi: 10.1016/s1046-5928(02)00516-8. Protein Expr Purif. 2002. PMID: 12356481

9

The mouse surfeit locus contains a very tight cluster of four "housekeeping" genes that is conserved through evolution.

Williams T, Yon J, Huxley C, Fried M. Williams T, et al. Among authors: yon j. Proc Natl Acad Sci U S A. 1988 May;85(10):3527-30. doi: 10.1073/pnas.85.10.3527. Proc Natl Acad Sci U S A. 1988. PMID: 2453062 Free PMC article.

10

Conservation of the organization of five tightly clustered genes over 600 million years of divergent evolution.

Colombo P, Yon J, Garson K, Fried M. Colombo P, et al. Among authors: yon j. Proc Natl Acad Sci U S A. 1992 Jul 15;89(14):6358-62. doi: 10.1073/pnas.89.14.6358. Proc Natl Acad Sci U S A. 1992. PMID: 1631131 Free PMC article.

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