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Predictive Modeling of Tacrolimus Dose Requirement Based on High-Throughput Genetic Screening.
Damon C, Luck M, Toullec L, Etienne I, Buchler M, Hurault de Ligny B, Choukroun G, Thierry A, Vigneau C, Moulin B, Heng AE, Subra JF, Legendre C, Monnot A, Yartseva A, Bateson M, Laurent-Puig P, Anglicheau D, Beaune P, Loriot MA, Thervet E, Pallet N. Damon C, et al. Among authors: beaune p. Am J Transplant. 2017 Apr;17(4):1008-1019. doi: 10.1111/ajt.14040. Epub 2016 Oct 7. Am J Transplant. 2017. PMID: 27597269 Free article. Clinical Trial.
A Lack of Significant Effect of POR*28 Allelic Variant on Tacrolimus Exposure in Kidney Transplant Recipients.
Jannot AS, Vuillemin X, Etienne I, Buchler M, Hurault de Ligny B, Choukroun G, Colosio C, Thierry A, Vigneau C, Moulin B, Rerolle JP, Heng AE, Subra JF, Legendre C, Beaune P, Loriot MA, Thervet E, Pallet N. Jannot AS, et al. Among authors: beaune p. Ther Drug Monit. 2016 Apr;38(2):223-9. doi: 10.1097/FTD.0000000000000267. Ther Drug Monit. 2016. PMID: 26829596 Clinical Trial.
Kidney transplant recipients carrying the CYP3A4*22 allelic variant have reduced tacrolimus clearance and often reach supratherapeutic tacrolimus concentrations.
Pallet N, Jannot AS, El Bahri M, Etienne I, Buchler M, de Ligny BH, Choukroun G, Colosio C, Thierry A, Vigneau C, Moulin B, Le Meur Y, Heng AE, Subra JF, Legendre C, Beaune P, Alberti C, Loriot MA, Thervet E. Pallet N, et al. Among authors: beaune p. Am J Transplant. 2015 Mar;15(3):800-5. doi: 10.1111/ajt.13059. Epub 2015 Jan 14. Am J Transplant. 2015. PMID: 25588704 Free article.
Long-Term Clinical Impact of Adaptation of Initial Tacrolimus Dosing to CYP3A5 Genotype.
Pallet N, Etienne I, Buchler M, Bailly E, Hurault de Ligny B, Choukroun G, Colosio C, Thierry A, Vigneau C, Moulin B, Le Meur Y, Heng AE, Legendre C, Beaune P, Loriot MA, Thervet E. Pallet N, et al. Among authors: beaune p. Am J Transplant. 2016 Sep;16(9):2670-5. doi: 10.1111/ajt.13788. Epub 2016 Apr 8. Am J Transplant. 2016. PMID: 26990694 Free article.
330 results