Kumari S - Search Results

1

A DOCK8-WIP-WASp complex links T cell receptors to the actin cytoskeleton.

Janssen E, Tohme M, Hedayat M, Leick M, Kumari S, Ramesh N, Massaad MJ, Ullas S, Azcutia V, Goodnow CC, Randall KL, Qiao Q, Wu H, Al-Herz W, Cox D, Hartwig J, Irvine DJ, Luscinskas FW, Geha RS. Janssen E, et al. Among authors: kumari s. J Clin Invest. 2016 Oct 3;126(10):3837-3851. doi: 10.1172/JCI85774. Epub 2016 Sep 6. J Clin Invest. 2016. PMID: 27599296 Free PMC article.

2

Actin foci facilitate activation of the phospholipase C-γ in primary T lymphocytes via the WASP pathway.

Kumari S, Depoil D, Martinelli R, Judokusumo E, Carmona G, Gertler FB, Kam LC, Carman CV, Burkhardt JK, Irvine DJ, Dustin ML. Kumari S, et al. Elife. 2015 Mar 11;4:e04953. doi: 10.7554/eLife.04953. Elife. 2015. PMID: 25758716 Free PMC article.

3

Enhancing Adoptive Cell Therapy of Cancer through Targeted Delivery of Small-Molecule Immunomodulators to Internalizing or Noninternalizing Receptors.

Zheng Y, Tang L, Mabardi L, Kumari S, Irvine DJ. Zheng Y, et al. Among authors: kumari s. ACS Nano. 2017 Mar 28;11(3):3089-3100. doi: 10.1021/acsnano.7b00078. Epub 2017 Mar 1. ACS Nano. 2017. PMID: 28231431 Free PMC article.

4

DOCK8 enforces immunological tolerance by promoting IL-2 signaling and immune synapse formation in Tregs.

Janssen E, Kumari S, Tohme M, Ullas S, Barrera V, Tas JM, Castillo-Rama M, Bronson RT, Usmani SM, Irvine DJ, Mempel TR, Geha RS. Janssen E, et al. Among authors: kumari s. JCI Insight. 2017 Oct 5;2(19):e94298. doi: 10.1172/jci.insight.94298. JCI Insight. 2017. PMID: 28978806 Free PMC article.

5

Not All T Cell Synapses Are Built the Same Way.

Kumari S, Colin-York H, Irvine DJ, Fritzsche M. Kumari S, et al. Trends Immunol. 2019 Nov;40(11):977-980. doi: 10.1016/j.it.2019.09.009. Epub 2019 Oct 20. Trends Immunol. 2019. PMID: 31645298 Free PMC article. Review.

6

DOCK2 Sets the Threshold for Entry into the Virtual Memory CD8⁺ T Cell Compartment by Negatively Regulating Tonic TCR Triggering.

Mahajan VS, Demissie E, Alsufyani F, Kumari S, Yuen GJ, Viswanadham V, Huang A, Tran JQ, Moon JJ, Irvine DJ, Pillai S. Mahajan VS, et al. Among authors: kumari s. J Immunol. 2020 Jan 1;204(1):49-57. doi: 10.4049/jimmunol.1900440. Epub 2019 Nov 18. J Immunol. 2020. PMID: 31740487 Free PMC article.

7

Cytoskeletal tension actively sustains the migratory T-cell synaptic contact.

Kumari S, Mak M, Poh YC, Tohme M, Watson N, Melo M, Janssen E, Dustin M, Geha R, Irvine DJ. Kumari S, et al. EMBO J. 2020 Mar 2;39(5):e102783. doi: 10.15252/embj.2019102783. Epub 2020 Jan 2. EMBO J. 2020. PMID: 31894880 Free PMC article.

8

T cell antigen receptor activation and actin cytoskeleton remodeling.

Kumari S, Curado S, Mayya V, Dustin ML. Kumari S, et al. Biochim Biophys Acta. 2014 Feb;1838(2):546-56. doi: 10.1016/j.bbamem.2013.05.004. Epub 2013 May 14. Biochim Biophys Acta. 2014. PMID: 23680625 Free PMC article. Review.

9

Antigen recognition-triggered drug delivery mediated by nanocapsule-functionalized cytotoxic T-cells.

Jones RB, Mueller S, Kumari S, Vrbanac V, Genel S, Tager AM, Allen TM, Walker BD, Irvine DJ. Jones RB, et al. Among authors: kumari s. Biomaterials. 2017 Feb;117:44-53. doi: 10.1016/j.biomaterials.2016.11.048. Epub 2016 Nov 25. Biomaterials. 2017. PMID: 27936416 Free PMC article.

10

Sustained antigen availability during germinal center initiation enhances antibody responses to vaccination.

Tam HH, Melo MB, Kang M, Pelet JM, Ruda VM, Foley MH, Hu JK, Kumari S, Crampton J, Baldeon AD, Sanders RW, Moore JP, Crotty S, Langer R, Anderson DG, Chakraborty AK, Irvine DJ. Tam HH, et al. Among authors: kumari s. Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):E6639-E6648. doi: 10.1073/pnas.1606050113. Epub 2016 Oct 4. Proc Natl Acad Sci U S A. 2016. PMID: 27702895 Free PMC article.

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