Jardim GA - Search Results

1

Rh-Catalyzed Reactions of 1,4-Benzoquinones with Electrophiles: C-H Iodination, Bromination, and Phenylselenation.

Jardim GA, Bower JF, da Silva Júnior EN. Jardim GA, et al. Org Lett. 2016 Sep 16;18(18):4454-7. doi: 10.1021/acs.orglett.6b01586. Epub 2016 Sep 7. Org Lett. 2016. PMID: 27599589

2

Overcoming naphthoquinone deactivation: rhodium-catalyzed C-5 selective C-H iodination as a gateway to functionalized derivatives.

Jardim GAM, da Silva Júnior EN, Bower JF. Jardim GAM, et al. Chem Sci. 2016 Jun 1;7(6):3780-3784. doi: 10.1039/c6sc00302h. Epub 2016 Mar 2. Chem Sci. 2016. PMID: 30155019 Free PMC article.

3

Rhodium-catalyzed C-H bond activation for the synthesis of quinonoid compounds: Significant Anti-Trypanosoma cruzi activities and electrochemical studies of functionalized quinones.

Jardim GAM, Silva TL, Goulart MOF, de Simone CA, Barbosa JMC, Salomão K, de Castro SL, Bower JF, da Silva Júnior EN. Jardim GAM, et al. Eur J Med Chem. 2017 Aug 18;136:406-419. doi: 10.1016/j.ejmech.2017.05.011. Epub 2017 May 4. Eur J Med Chem. 2017. PMID: 28521262

4

Synthesis of Selenium-Quinone Hybrid Compounds with Potential Antitumor Activity via Rh-Catalyzed C-H Bond Activation and Click Reactions.

Jardim GAM, Lima DJB, Valença WO, Lima DJB, Cavalcanti BC, Pessoa C, Rafique J, Braga AL, Jacob C, da Silva Júnior EN, da Cruz EHG. Jardim GAM, et al. Molecules. 2017 Dec 30;23(1):83. doi: 10.3390/molecules23010083. Molecules. 2017. PMID: 29301214 Free PMC article.

5

Direct sequential C-H iodination/organoyl-thiolation for the benzenoid A-ring modification of quinonoid deactivated systems: a new protocol for potent trypanocidal quinones.

Jardim GAM, Oliveira WXC, de Freitas RP, Menna-Barreto RFS, Silva TL, Goulart MOF, da Silva Júnior EN. Jardim GAM, et al. Org Biomol Chem. 2018 Mar 7;16(10):1686-1691. doi: 10.1039/c8ob00196k. Org Biomol Chem. 2018. PMID: 29450434

6

Synthesis and antitumor activity of selenium-containing quinone-based triazoles possessing two redox centres, and their mechanistic insights.

da Cruz EHG, Silvers MA, Jardim GAM, Resende JM, Cavalcanti BC, Bomfim IS, Pessoa C, de Simone CA, Botteselle GV, Braga AL, Nair DK, Namboothiri INN, Boothman DA, da Silva Júnior EN. da Cruz EHG, et al. Eur J Med Chem. 2016 Oct 21;122:1-16. doi: 10.1016/j.ejmech.2016.06.019. Epub 2016 Jun 14. Eur J Med Chem. 2016. PMID: 27341379 Free PMC article.

7

Indirect consequences of exciplex states on the phosphorescence lifetime of phenazine-based 1,2,3-triazole luminescent probes.

Costa BB, Jardim GA, Santos PL, Calado HD, Monkman AP, Dias FB, da Silva Júnior EN, Cury LA. Costa BB, et al. Among authors: jardim ga. Phys Chem Chem Phys. 2017 Feb 1;19(5):3473-3479. doi: 10.1039/c6cp06134f. Phys Chem Chem Phys. 2017. PMID: 27824176

8

Weakly-coordinating N-oxide and carbonyl groups for metal-catalyzed C-H activation: the case of A-ring functionalization.

da Silva Júnior EN , Jardim GAM , Gomes RS , Liang YF , Ackermann L . da Silva Júnior EN , et al. Chem Commun (Camb). 2018 Jul 3;54(54):7398-7411. doi: 10.1039/c8cc03147a. Chem Commun (Camb). 2018. PMID: 29863215

9

Combination of Aryl Diselenides/Hydrogen Peroxide and Carbon-Nanotube/Rhodium Nanohybrids for Naphthol Oxidation: An Efficient Route towards Trypanocidal Quinones.

de Carvalho RL, Jardim GAM, Santos ACC, Araujo MH, Oliveira WXC, Bombaça ACS, Menna-Barreto RFS, Gopi E, Gravel E, Doris E, da Silva Júnior EN. de Carvalho RL, et al. Chemistry. 2018 Oct 12;24(57):15227-15235. doi: 10.1002/chem.201802773. Epub 2018 Sep 6. Chemistry. 2018. PMID: 29904959

10

Synthesis of quinones with highlighted biological applications: A critical update on the strategies towards bioactive compounds with emphasis on lapachones.

da Silva Júnior EN, Jardim GAM, Jacob C, Dhawa U, Ackermann L, de Castro SL. da Silva Júnior EN, et al. Eur J Med Chem. 2019 Oct 1;179:863-915. doi: 10.1016/j.ejmech.2019.06.056. Epub 2019 Jun 25. Eur J Med Chem. 2019. PMID: 31306817 Review.

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