Umezawa K - Search Results

1

Inhibition of nuclear factor-κB signaling suppresses Spint1-deletion-induced tumor susceptibility in the ApcMin/+ model.

Kawaguchi M, Yamamoto K, Kanemaru A, Tanaka H, Umezawa K, Fukushima T, Kataoka H. Kawaguchi M, et al. Among authors: umezawa k. Oncotarget. 2016 Oct 18;7(42):68614-68622. doi: 10.18632/oncotarget.11863. Oncotarget. 2016. PMID: 27612426 Free PMC article.

2

Antitumor effect of dehydroxymethylepoxyquinomicin, a small molecule inhibitor of nuclear factor-κB, on glioblastoma.

Fukushima T, Kawaguchi M, Yorita K, Tanaka H, Takeshima H, Umezawa K, Kataoka H. Fukushima T, et al. Among authors: umezawa k. Neuro Oncol. 2012 Jan;14(1):19-28. doi: 10.1093/neuonc/nor168. Epub 2011 Oct 3. Neuro Oncol. 2012. PMID: 21968049 Free PMC article.

3

Inhibition of receptor activator of nuclear factor-κB ligand- or lipopolysaccharide-induced osteoclast formation by conophylline through downregulation of CREB.

Koide N, Kondo Y, Odkhuu E, Ulziisaikhan J, Ukaji T, Yokochi T, Umezawa K. Koide N, et al. Among authors: umezawa k. Immunol Lett. 2014 Sep;161(1):31-7. doi: 10.1016/j.imlet.2014.04.006. Epub 2014 May 2. Immunol Lett. 2014. PMID: 24792671

4

Novel approaches to target NF-κB and other signaling pathways in cancer stem cells.

Ukaji T, Umezawa K. Ukaji T, et al. Among authors: umezawa k. Adv Biol Regul. 2014 Sep;56:108-15. doi: 10.1016/j.jbior.2014.06.001. Epub 2014 Jul 1. Adv Biol Regul. 2014. PMID: 25128192 Review.

5

Aberrant expression of NF-κB in liver fluke associated cholangiocarcinoma: implications for targeted therapy.

Seubwai W, Wongkham C, Puapairoj A, Khuntikeo N, Pugkhem A, Hahnvajanawong C, Chaiyagool J, Umezawa K, Okada S, Wongkham S. Seubwai W, et al. Among authors: umezawa k. PLoS One. 2014 Aug 29;9(8):e106056. doi: 10.1371/journal.pone.0106056. eCollection 2014. PLoS One. 2014. PMID: 25170898 Free PMC article.

6

A nuclear factor-κB inhibitor, dehydroxymethylepoxyquinomicin, ameliorates GVHD in allogeneic bone marrow transplantation.

Yamanouchi S, Adachi Y, Shimo T, Umezawa K, Okigaki M, Tsuji S, Li M, Takaya J, Kuge T, Ikehara S, Kaneko K. Yamanouchi S, et al. Among authors: umezawa k. Immunobiology. 2015 Sep;220(9):1059-66. doi: 10.1016/j.imbio.2015.05.011. Epub 2015 May 11. Immunobiology. 2015. PMID: 26004346

7

Effects of AP‑1 and NF‑κB inhibitors on colonic endocrine cells in rats with TNBS‑induced colitis.

El-Salhy M, Umezawa K. El-Salhy M, et al. Among authors: umezawa k. Mol Med Rep. 2016 Aug;14(2):1515-22. doi: 10.3892/mmr.2016.5444. Epub 2016 Jun 27. Mol Med Rep. 2016. PMID: 27357734 Free PMC article.

8

Inhibition of MMP-2-mediated cellular invasion by NF-κB inhibitor DHMEQ in 3D culture of breast carcinoma MDA-MB-231 cells: A model for early phase of metastasis.

Ukaji T, Lin Y, Okada S, Umezawa K. Ukaji T, et al. Among authors: umezawa k. Biochem Biophys Res Commun. 2017 Mar 25;485(1):76-81. doi: 10.1016/j.bbrc.2017.02.022. Epub 2017 Feb 8. Biochem Biophys Res Commun. 2017. PMID: 28188787

9

External application of NF-κB inhibitor DHMEQ suppresses development of atopic dermatitis-like lesions induced with DNCB/OX in BALB/c mice.

Jiang X, Lan Y, Wei B, Dai C, Gu Y, Ma J, Liu X, Umezawa K, Zhang Y. Jiang X, et al. Among authors: umezawa k. Immunopharmacol Immunotoxicol. 2017 Jun;39(3):157-164. doi: 10.1080/08923973.2017.1312436. Immunopharmacol Immunotoxicol. 2017. PMID: 28418286

10

Antineoplastic Effects of NF-κB Inhibition by DHMEQ (Dehydroxymethylepoxyquinomicin) Alone and in Co-treatment with Radio-and Chemotherapy in Medulloblastoma Cell Lines.

Ramos PMM, Pezuk JA, Castro-Gamero AM, Oliveira HF, Scrideli CA, Umezawa K, Tone LG. Ramos PMM, et al. Among authors: umezawa k. Anticancer Agents Med Chem. 2018;18(4):541-549. doi: 10.2174/1871520617666171113151335. Anticancer Agents Med Chem. 2018. PMID: 29141555

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