Froeyen M - Search Results

1

Elaboration of a proprietary thymidylate kinase inhibitor motif towards anti-tuberculosis agents.

Song L, Risseeuw MDP, Froeyen M, Karalic I, Goeman J, Cappoen D, Van der Eycken J, Cos P, Munier-Lehmann H, Van Calenbergh S. Song L, et al. Among authors: froeyen m. Bioorg Med Chem. 2016 Nov 1;24(21):5172-5182. doi: 10.1016/j.bmc.2016.08.041. Epub 2016 Aug 24. Bioorg Med Chem. 2016. PMID: 27614917 Free article.

2

3'-C-branched-chain-substituted nucleosides and nucleotides as potent inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase.

Vanheusden V, Munier-Lehmann H, Froeyen M, Dugué L, Heyerick A, De Keukeleire D, Pochet S, Busson R, Herdewijn P, Van Calenbergh S. Vanheusden V, et al. Among authors: froeyen m. J Med Chem. 2003 Aug 28;46(18):3811-21. doi: 10.1021/jm021108n. J Med Chem. 2003. PMID: 12930144 Free article.

3

Discovery of bicyclic thymidine analogues as selective and high-affinity inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase.

Vanheusden V, Munier-Lehmann H, Froeyen M, Busson R, Rozenski J, Herdewijn P, Van Calenbergh S. Vanheusden V, et al. Among authors: froeyen m. J Med Chem. 2004 Dec 2;47(25):6187-94. doi: 10.1021/jm040847w. J Med Chem. 2004. PMID: 15566289

4

Synthesis and biological evaluation of bicyclic nucleosides as inhibitors of M. tuberculosis thymidylate kinase.

Van Daele I, Munier-Lehmann H, Hendrickx PM, Marchal G, Chavarot P, Froeyen M, Qing L, Martins JC, Van Calenbergh S. Van Daele I, et al. Among authors: froeyen m. ChemMedChem. 2006 Oct;1(10):1081-90. doi: 10.1002/cmdc.200600028. ChemMedChem. 2006. PMID: 16921580

5

Rational design of 5'-thiourea-substituted alpha-thymidine analogues as thymidine monophosphate kinase inhibitors capable of inhibiting mycobacterial growth.

Van Daele I, Munier-Lehmann H, Froeyen M, Balzarini J, Van Calenbergh S. Van Daele I, et al. Among authors: froeyen m. J Med Chem. 2007 Nov 1;50(22):5281-92. doi: 10.1021/jm0706158. Epub 2007 Oct 2. J Med Chem. 2007. PMID: 17910427

6

Synthesis and inhibitory activity of thymidine analogues targeting Mycobacterium tuberculosis thymidine monophosphate kinase.

Van Poecke S, Munier-Lehmann H, Helynck O, Froeyen M, Van Calenbergh S. Van Poecke S, et al. Among authors: froeyen m. Bioorg Med Chem. 2011 Dec 15;19(24):7603-11. doi: 10.1016/j.bmc.2011.10.021. Epub 2011 Oct 18. Bioorg Med Chem. 2011. PMID: 22061826

7

Molecular simulation of cyclohexanyl nucleic acid (CNA) duplexes with CNA, DNA and RNA and CNA triloop and tetraloop hairpin structures.

Froeyen M, Abu el Asrar R, Abramov M, Herdewijn P. Froeyen M, et al. Bioorg Med Chem. 2016 Apr 15;24(8):1778-85. doi: 10.1016/j.bmc.2016.03.007. Epub 2016 Mar 3. Bioorg Med Chem. 2016. PMID: 26968651

8

Corrigenda to "Elaboration of a proprietary thymidylate kinase inhibitor motif towards anti-tuberculosis agents" [Bioorg Med Chem 24 (2016) 5172-5182].

Song L, Risseeuw MDP, Froeyen M, Karalic I, Goeman J, Cappoen D, Van der Eycken J, Cos P, Munier-Lehmann H, Van Calenbergh S. Song L, et al. Among authors: froeyen m. Bioorg Med Chem. 2017 Oct 15;25(20):5889. doi: 10.1016/j.bmc.2017.08.023. Epub 2017 Aug 18. Bioorg Med Chem. 2017. PMID: 28826595 No abstract available.

9

Family-wide analysis of aminoacyl-sulfamoyl-3-deazaadenosine analogues as inhibitors of aminoacyl-tRNA synthetases.

Zhang B, De Graef S, Nautiyal M, Pang L, Gadakh B, Froeyen M, Van Mellaert L, Strelkov SV, Weeks SD, Van Aerschot A. Zhang B, et al. Among authors: froeyen m. Eur J Med Chem. 2018 Mar 25;148:384-396. doi: 10.1016/j.ejmech.2018.02.013. Epub 2018 Feb 14. Eur J Med Chem. 2018. PMID: 29477072

10

In vitro evaluation of arylsubstituted imidazoles derivatives as antiprotozoal agents and docking studies on sterol 14α-demethylase (CYP51) from Trypanosoma cruzi, Leishmania infantum, and Trypanosoma brucei.

Rojas Vargas JA, López AG, Pérez Y, Cos P, Froeyen M. Rojas Vargas JA, et al. Among authors: froeyen m. Parasitol Res. 2019 May;118(5):1533-1548. doi: 10.1007/s00436-019-06206-z. Epub 2019 Mar 23. Parasitol Res. 2019. PMID: 30903349

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

133 results

Search Page

Filters