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Structure-based design, parallel synthesis, structure-activity relationship, and molecular modeling studies of thiocarbamates, new potent non-nucleoside HIV-1 reverse transcriptase inhibitor isosteres of phenethylthiazolylthiourea derivatives.
Ranise A, Spallarossa A, Cesarini S, Bondavalli F, Schenone S, Bruno O, Menozzi G, Fossa P, Mosti L, La Colla M, Sanna G, Murreddu M, Collu G, Busonera B, Marongiu ME, Pani A, La Colla P, Loddo R. Ranise A, et al. Among authors: loddo r. J Med Chem. 2005 Jun 2;48(11):3858-73. doi: 10.1021/jm049252r. J Med Chem. 2005. PMID: 15916438
Thiocarbamates as non-nucleoside HIV-1 reverse transcriptase inhibitors. Part 1: Parallel synthesis, molecular modelling and structure-activity relationship studies on O-[2-(hetero)arylethyl]-N-phenylthiocarbamates.
Cesarini S, Spallarossa A, Ranise A, Fossa P, La Colla P, Sanna G, Collu G, Loddo R. Cesarini S, et al. Among authors: loddo r. Bioorg Med Chem. 2008 Apr 1;16(7):4160-72. doi: 10.1016/j.bmc.2007.12.050. Epub 2007 Dec 25. Bioorg Med Chem. 2008. PMID: 18226532
Parallel one-pot synthesis and structure-activity relationship study of symmetric formimidoester disulfides as a novel class of potent non-nucleoside HIV-1 reverse transcriptase inhibitors.
Cesarini S, Spallarossa A, Ranise A, Schenone S, Bruno O, La Colla P, Casula L, Collu G, Sanna G, Loddo R. Cesarini S, et al. Among authors: loddo r. Bioorg Med Chem. 2008 Jun 15;16(12):6353-63. doi: 10.1016/j.bmc.2008.05.010. Epub 2008 May 7. Bioorg Med Chem. 2008. PMID: 18502646
101 results