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Loss-of-function mutations in the X-linked biglycan gene cause a severe syndromic form of thoracic aortic aneurysms and dissections.
Meester JA, Vandeweyer G, Pintelon I, Lammens M, Van Hoorick L, De Belder S, Waitzman K, Young L, Markham LW, Vogt J, Richer J, Beauchesne LM, Unger S, Superti-Furga A, Prsa M, Dhillon R, Reyniers E, Dietz HC, Wuyts W, Mortier G, Verstraeten A, Van Laer L, Loeys BL. Meester JA, et al. Among authors: young l. Genet Med. 2017 Apr;19(4):386-395. doi: 10.1038/gim.2016.126. Epub 2016 Sep 15. Genet Med. 2017. PMID: 27632686 Free PMC article.
Characteristics of children and young adults with Marfan syndrome and aortic root dilation in a randomized trial comparing atenolol and losartan therapy.
Lacro RV, Guey LT, Dietz HC, Pearson GD, Yetman AT, Gelb BD, Loeys BL, Benson DW, Bradley TJ, De Backer J, Forbus GA, Klein GL, Lai WW, Levine JC, Lewin MB, Markham LW, Paridon SM, Pierpont ME, Radojewski E, Selamet Tierney ES, Sharkey AM, Wechsler SB, Mahony L; Pediatric Heart Network Investigators. Lacro RV, et al. Am Heart J. 2013 May;165(5):828-835.e3. doi: 10.1016/j.ahj.2013.02.019. Epub 2013 Mar 26. Am Heart J. 2013. PMID: 23622922 Free PMC article. Clinical Trial.
Atenolol versus losartan in children and young adults with Marfan's syndrome.
Lacro RV, Dietz HC, Sleeper LA, Yetman AT, Bradley TJ, Colan SD, Pearson GD, Selamet Tierney ES, Levine JC, Atz AM, Benson DW, Braverman AC, Chen S, De Backer J, Gelb BD, Grossfeld PD, Klein GL, Lai WW, Liou A, Loeys BL, Markham LW, Olson AK, Paridon SM, Pemberton VL, Pierpont ME, Pyeritz RE, Radojewski E, Roman MJ, Sharkey AM, Stylianou MP, Wechsler SB, Young LT, Mahony L; Pediatric Heart Network Investigators. Lacro RV, et al. Among authors: young lt. N Engl J Med. 2014 Nov 27;371(22):2061-71. doi: 10.1056/NEJMoa1404731. Epub 2014 Nov 18. N Engl J Med. 2014. PMID: 25405392 Free PMC article. Clinical Trial.
Health-Related Quality of Life in Children and Young Adults with Marfan Syndrome.
Handisides JC, Hollenbeck-Pringle D, Uzark K, Trachtenberg FL, Pemberton VL, Atz TW, Bradley TJ, Cappella E, De Nobele S, Groh GK, Hamstra MS, Korsin R, Levine JC, Lindauer B, Liou A, Neal MKM, Markham LW, Morrison T, Mussatto KA, Olson AK, Pierpont MEM, Pyeritz RE, Radojewski EA, Roman MJ, Xu M, Lacro RV; Pediatric Heart Network Investigators. Handisides JC, et al. J Pediatr. 2019 Jan;204:250-255.e1. doi: 10.1016/j.jpeds.2018.08.061. Epub 2018 Sep 27. J Pediatr. 2019. PMID: 30270167 Free PMC article. Clinical Trial.
Predictors of Bicuspid Aortic Valve-Associated Aortopathy in Childhood: A Report From the MIBAVA Consortium.
Grattan M, Prince A, Rumman RK, Morgan C, Petrovic M, Hauck A, Young L, Franco-Cereceda A, Loeys B, Mohamed SA, Dietz H, Mital S, Fan CS, Manlhiot C, Andelfinger G, Mertens L. Grattan M, et al. Among authors: young l. Circ Cardiovasc Imaging. 2020 Mar;13(3):e009717. doi: 10.1161/CIRCIMAGING.119.009717. Epub 2020 Mar 17. Circ Cardiovasc Imaging. 2020. PMID: 32178537
Variants in ADRB1 and CYP2C9: Association with Response to Atenolol and Losartan in Marfan Syndrome.
Van Driest SL, Sleeper LA, Gelb BD, Morris SA, Dietz HC, Forbus GA, Goldmuntz E, Hoskoppal A, James J, Lee TM, Levine JC, Li JS, Loeys BL, Markham LW, Meester JAN, Mital S, Mosley JD, Olson AK, Renard M, Shaffer CM, Sharkey A, Young L, Lacro RV, Roden DM. Van Driest SL, et al. Among authors: young l. J Pediatr. 2020 Jul;222:213-220.e5. doi: 10.1016/j.jpeds.2020.03.064. J Pediatr. 2020. PMID: 32586526 Free PMC article. Clinical Trial.
A unique cardiovascular presentation of Marfan syndrome.
Otero Luna A, Park KB, Schauer J, Castera M, Quintana Grijalba C, Chikkabyrappa SM, Tjoeng YL, Romberg EK, Olson A, Glass IA, Young L. Otero Luna A, et al. Among authors: young l. Am J Med Genet A. 2022 Aug;188(8):2443-2447. doi: 10.1002/ajmg.a.62865. Epub 2022 Jun 9. Am J Med Genet A. 2022. PMID: 35679177
Influence of Aortic Stiffness on Aortic-Root Growth Rate and Outcome in Patients With the Marfan Syndrome.
Selamet Tierney ES, Levine JC, Sleeper LA, Roman MJ, Bradley TJ, Colan SD, Chen S, Campbell MJ, Cohen MS, De Backer J, Heydarian H, Hoskoppal A, Lai WW, Liou A, Marcus E, Nutting A, Olson AK, Parra DA, Pearson GD, Pierpont ME, Printz BF, Pyeritz RE, Ravekes W, Sharkey AM, Srivastava S, Young L, Lacro RV; Pediatric Heart Network Investigators. Selamet Tierney ES, et al. Among authors: young l. Am J Cardiol. 2018 May 1;121(9):1094-1101. doi: 10.1016/j.amjcard.2018.01.016. Epub 2018 Feb 13. Am J Cardiol. 2018. PMID: 29631804 Free PMC article. Clinical Trial.
Altered aortic 3D hemodynamics and geometry in pediatric Marfan syndrome patients.
van der Palen RL, Barker AJ, Bollache E, Garcia J, Rose MJ, van Ooij P, Young LT, Roest AA, Markl M, Robinson JD, Rigsby CK. van der Palen RL, et al. Among authors: young lt. J Cardiovasc Magn Reson. 2017 Mar 17;19(1):30. doi: 10.1186/s12968-017-0345-7. J Cardiovasc Magn Reson. 2017. PMID: 28302143 Free PMC article.
5,153 results