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Determining crystal structures through crowdsourcing and coursework.
Horowitz S, Koepnick B, Martin R, Tymieniecki A, Winburn AA, Cooper S, Flatten J, Rogawski DS, Koropatkin NM, Hailu TT, Jain N, Koldewey P, Ahlstrom LS, Chapman MR, Sikkema AP, Skiba MA, Maloney FP, Beinlich FR; Foldit Players; University of Michigan students; Popović Z, Baker D, Khatib F, Bardwell JC. Horowitz S, et al. Among authors: baker d. Nat Commun. 2016 Sep 16;7:12549. doi: 10.1038/ncomms12549. Nat Commun. 2016. PMID: 27633552 Free PMC article.
Kemp elimination catalysts by computational enzyme design.
Röthlisberger D, Khersonsky O, Wollacott AM, Jiang L, DeChancie J, Betker J, Gallaher JL, Althoff EA, Zanghellini A, Dym O, Albeck S, Houk KN, Tawfik DS, Baker D. Röthlisberger D, et al. Among authors: baker d. Nature. 2008 May 8;453(7192):190-5. doi: 10.1038/nature06879. Epub 2008 Mar 19. Nature. 2008. PMID: 18354394
Predicting protein structures with a multiplayer online game.
Cooper S, Khatib F, Treuille A, Barbero J, Lee J, Beenen M, Leaver-Fay A, Baker D, Popović Z, Players F. Cooper S, et al. Among authors: baker d. Nature. 2010 Aug 5;466(7307):756-60. doi: 10.1038/nature09304. Nature. 2010. PMID: 20686574 Free PMC article.
Crystal structure of a monomeric retroviral protease solved by protein folding game players.
Khatib F, DiMaio F; Foldit Contenders Group; Foldit Void Crushers Group; Cooper S, Kazmierczyk M, Gilski M, Krzywda S, Zabranska H, Pichova I, Thompson J, Popović Z, Jaskolski M, Baker D. Khatib F, et al. Among authors: baker d. Nat Struct Mol Biol. 2011 Sep 18;18(10):1175-7. doi: 10.1038/nsmb.2119. Nat Struct Mol Biol. 2011. PMID: 21926992 Free PMC article.
Algorithm discovery by protein folding game players.
Khatib F, Cooper S, Tyka MD, Xu K, Makedon I, Popovic Z, Baker D, Players F. Khatib F, et al. Among authors: baker d. Proc Natl Acad Sci U S A. 2011 Nov 22;108(47):18949-53. doi: 10.1073/pnas.1115898108. Epub 2011 Nov 7. Proc Natl Acad Sci U S A. 2011. PMID: 22065763 Free PMC article.
5,816 results