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The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome.
Sebaihia M, Wren BW, Mullany P, Fairweather NF, Minton N, Stabler R, Thomson NR, Roberts AP, Cerdeño-Tárraga AM, Wang H, Holden MT, Wright A, Churcher C, Quail MA, Baker S, Bason N, Brooks K, Chillingworth T, Cronin A, Davis P, Dowd L, Fraser A, Feltwell T, Hance Z, Holroyd S, Jagels K, Moule S, Mungall K, Price C, Rabbinowitsch E, Sharp S, Simmonds M, Stevens K, Unwin L, Whithead S, Dupuy B, Dougan G, Barrell B, Parkhill J. Sebaihia M, et al. Nat Genet. 2006 Jul;38(7):779-86. doi: 10.1038/ng1830. Epub 2006 Jun 25. Nat Genet. 2006. PMID: 16804543
The ClosTron: Mutagenesis in Clostridium refined and streamlined.
Heap JT, Kuehne SA, Ehsaan M, Cartman ST, Cooksley CM, Scott JC, Minton NP. Heap JT, et al. Among authors: minton np. J Microbiol Methods. 2010 Jan;80(1):49-55. doi: 10.1016/j.mimet.2009.10.018. Epub 2009 Nov 3. J Microbiol Methods. 2010. PMID: 19891996
The emergence of 'hypervirulence' in Clostridium difficile.
Cartman ST, Heap JT, Kuehne SA, Cockayne A, Minton NP. Cartman ST, et al. Among authors: minton np. Int J Med Microbiol. 2010 Aug;300(6):387-95. doi: 10.1016/j.ijmm.2010.04.008. Epub 2010 May 23. Int J Med Microbiol. 2010. PMID: 20547099 Review.
ClosTron-targeted mutagenesis.
Heap JT, Cartman ST, Kuehne SA, Cooksley C, Minton NP. Heap JT, et al. Among authors: minton np. Methods Mol Biol. 2010;646:165-82. doi: 10.1007/978-1-60327-365-7_11. Methods Mol Biol. 2010. PMID: 20597009
Clostridium difficile spore germination: an update.
Burns DA, Heap JT, Minton NP. Burns DA, et al. Among authors: minton np. Res Microbiol. 2010 Nov;161(9):730-4. doi: 10.1016/j.resmic.2010.09.007. Epub 2010 Sep 21. Res Microbiol. 2010. PMID: 20863888 Free article. Review.
243 results