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Multivalent Chromatin Engagement and Inter-domain Crosstalk Regulate MORC3 ATPase.
Andrews FH, Tong Q, Sullivan KD, Cornett EM, Zhang Y, Ali M, Ahn J, Pandey A, Guo AH, Strahl BD, Costello JC, Espinosa JM, Rothbart SB, Kutateladze TG. Andrews FH, et al. Among authors: costello jc. Cell Rep. 2016 Sep 20;16(12):3195-3207. doi: 10.1016/j.celrep.2016.08.050. Cell Rep. 2016. PMID: 27653685 Free PMC article.
Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors.
Powers RK, Culp-Hill R, Ludwig MP, Smith KP, Waugh KA, Minter R, Tuttle KD, Lewis HC, Rachubinski AL, Granrath RE, Carmona-Iragui M, Wilkerson RB, Kahn DE, Joshi M, Lleó A, Blesa R, Fortea J, D'Alessandro A, Costello JC, Sullivan KD, Espinosa JM. Powers RK, et al. Among authors: costello jc. Nat Commun. 2019 Oct 18;10(1):4766. doi: 10.1038/s41467-019-12739-9. Nat Commun. 2019. PMID: 31628327 Free PMC article.
Down syndrome is associated with altered frequency and functioning of tracheal multiciliated cells, and response to influenza virus infection.
Thomas SN, Niemeyer BF, Jimenez-Valdes RJ, Kaiser AJ, Espinosa JM, Sullivan KD, Goodspeed A, Costello JC, Alder JK, Cañas-Arranz R, García-Sastre A, Benam KH. Thomas SN, et al. Among authors: costello jc. iScience. 2023 Jul 14;26(8):107361. doi: 10.1016/j.isci.2023.107361. eCollection 2023 Aug 18. iScience. 2023. PMID: 37554445 Free PMC article.
Integrated analysis of immunometabolic interactions in Down syndrome.
Gillenwater LA, Galbraith MD, Rachubinski AL, Eduthan NP, Sullivan KD, Espinosa JM, Costello JC. Gillenwater LA, et al. Among authors: costello jc. Sci Adv. 2024 Dec 13;10(50):eadq3073. doi: 10.1126/sciadv.adq3073. Epub 2024 Dec 13. Sci Adv. 2024. PMID: 39671500 Free PMC article.
Next-Generation Machine Learning for Biological Networks.
Camacho DM, Collins KM, Powers RK, Costello JC, Collins JJ. Camacho DM, et al. Among authors: costello jc. Cell. 2018 Jun 14;173(7):1581-1592. doi: 10.1016/j.cell.2018.05.015. Epub 2018 Jun 7. Cell. 2018. PMID: 29887378 Free article. Review.
Coordinate loss of MAP3K7 and CHD1 promotes aggressive prostate cancer.
Rodrigues LU, Rider L, Nieto C, Romero L, Karimpour-Fard A, Loda M, Lucia MS, Wu M, Shi L, Cimic A, Sirintrapun SJ, Nolley R, Pac C, Chen H, Peehl DM, Xu J, Liu W, Costello JC, Cramer SD. Rodrigues LU, et al. Among authors: costello jc. Cancer Res. 2015 Mar 15;75(6):1021-34. doi: 10.1158/0008-5472.CAN-14-1596. Cancer Res. 2015. PMID: 25770290 Free PMC article.
92 results