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Antihypertensive effects of a highly potent and long-acting angiotensin II subtype-1 receptor antagonist, (+-)-1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H- benzimidazole-7-carboxylate (TCV-116), in various hypertensive rats.
Inada Y, Wada T, Shibouta Y, Ojima M, Sanada T, Ohtsuki K, Itoh K, Kubo K, Kohara Y, Naka T, et al. Inada Y, et al. Among authors: sanada t. J Pharmacol Exp Ther. 1994 Mar;268(3):1540-7. J Pharmacol Exp Ther. 1994. PMID: 8138966
Pharmacological profile of a highly potent and long-acting angiotensin II receptor antagonist, 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4- yl]methyl]-1H-benzimidazole-7-carboxylic acid (CV-11974), and its prodrug, (+/-)-1-(cyclohexyloxycarbonyloxy)-ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5- yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylate (TCV-116).
Shibouta Y, Inada Y, Ojima M, Wada T, Noda M, Sanada T, Kubo K, Kohara Y, Naka T, Nishikawa K. Shibouta Y, et al. Among authors: sanada t. J Pharmacol Exp Ther. 1993 Jul;266(1):114-20. J Pharmacol Exp Ther. 1993. PMID: 8331552
Discovery of a novel acyl-CoA: cholesterol acyltransferase inhibitor: the synthesis, biological evaluation, and reduced adrenal toxicity of (4-phenylcoumarin)acetanilide derivatives with a carboxylic acid moiety.
Ogino M, Nakada Y, Negoro N, Itokawa S, Nishimura S, Sanada T, Satomi T, Kita S, Kubo K, Marui S. Ogino M, et al. Among authors: sanada t. Chem Pharm Bull (Tokyo). 2011;59(11):1369-75. doi: 10.1248/cpb.59.1369. Chem Pharm Bull (Tokyo). 2011. PMID: 22041073 Free article.
320 results