Boraei AT - Search Results

1

Design, selective alkylation and X-ray crystal structure determination of dihydro-indolyl-1,2,4-triazole-3-thione and its 3-benzylsulfanyl analogue as potent anticancer agents.

Boraei AT, Gomaa MS, El Ashry ES, Duerkop A. Boraei AT, et al. Eur J Med Chem. 2017 Jan 5;125:360-371. doi: 10.1016/j.ejmech.2016.09.046. Epub 2016 Sep 15. Eur J Med Chem. 2017. PMID: 27688190

2

A new synthetic access to 2-N-(glycosyl)thiosemicarbazides from 3-N-(glycosyl)oxadiazolinethiones and the regioselectivity of the glycosylation of their oxadiazolinethione precursors.

El Ashry el SH, El Tamany el SH, Fattah Mel D, Aly MR, Boraei AT, Duerkop A. El Ashry el SH, et al. Among authors: boraei at. Beilstein J Org Chem. 2013;9:135-46. doi: 10.3762/bjoc.9.16. Epub 2013 Jan 21. Beilstein J Org Chem. 2013. PMID: 23400104 Free PMC article.

3

Regioselective synthesis, characterization and antimicrobial evaluation of S-glycosides and S,N-diglycosides of 1,2-Dihydro-5-(1H-indol-2-yl)-1,2,4-triazole-3-thione.

El Ashry el SH, El Tamany el SH, El Fattah Mel D, Boraei AT, Abd El-Nabi HM. El Ashry el SH, et al. Among authors: boraei at. Eur J Med Chem. 2013 Aug;66:106-13. doi: 10.1016/j.ejmech.2013.04.047. Epub 2013 May 20. Eur J Med Chem. 2013. PMID: 23792321

4

Regioselectivity of the alkylation of S-substituted 1,2,4-triazoles with dihaloalkanes.

Boraei AT, El Ashry el SH, Duerkop A. Boraei AT, et al. Chem Cent J. 2016 Apr 27;10:22. doi: 10.1186/s13065-016-0165-0. eCollection 2016. Chem Cent J. 2016. PMID: 27127538 Free PMC article.

5

Design and synthesis of new phthalazine-based derivatives as potential EGFR inhibitors for the treatment of hepatocellular carcinoma.

Boraei ATA, Ashour HK, El Tamany ESH, Abdelmoaty N, El-Falouji AI, Gomaa MS. Boraei ATA, et al. Bioorg Chem. 2019 Apr;85:293-307. doi: 10.1016/j.bioorg.2018.12.039. Epub 2018 Dec 31. Bioorg Chem. 2019. PMID: 30654221

6

Discovery of novel functionalized 1,2,4-triazoles as PARP-1 inhibitors in breast cancer: Design, synthesis and antitumor activity evaluation.

Boraei ATA, Singh PK, Sechi M, Satta S. Boraei ATA, et al. Eur J Med Chem. 2019 Nov 15;182:111621. doi: 10.1016/j.ejmech.2019.111621. Epub 2019 Aug 14. Eur J Med Chem. 2019. PMID: 31442685

7

Synthesis and Anti-Proliferative Assessment of Triazolo-Thiadiazepine and Triazolo-Thiadiazine Scaffolds.

Boraei ATA, Ghabbour HA, Gomaa MS, El Ashry ESH, Barakat A. Boraei ATA, et al. Molecules. 2019 Dec 6;24(24):4471. doi: 10.3390/molecules24244471. Molecules. 2019. PMID: 31817609 Free PMC article.

8

Discovery of New Apoptosis-Inducing Agents for Breast Cancer Based on Ethyl 2-Amino-4,5,6,7-Tetra Hydrobenzo[b]Thiophene-3-Carboxylate: Synthesis, In Vitro, and In Vivo Activity Evaluation.

Gad EM, Nafie MS, Eltamany EH, Hammad MSAG, Barakat A, Boraei ATA. Gad EM, et al. Among authors: boraei ata. Molecules. 2020 May 28;25(11):2523. doi: 10.3390/molecules25112523. Molecules. 2020. PMID: 32481682 Free PMC article.

9

Synthesis of new substituted pyridine derivatives as potent anti-liver cancer agents through apoptosis induction: In vitro, in vivo, and in silico integrated approaches.

Boraei ATA, Eltamany EH, Ali IAI, Gebriel SM, Nafie MS. Boraei ATA, et al. Bioorg Chem. 2021 Jun;111:104877. doi: 10.1016/j.bioorg.2021.104877. Epub 2021 Mar 29. Bioorg Chem. 2021. PMID: 33839579

10

Exploration of novel VEGFR2 tyrosine kinase inhibitors via design and synthesis of new alkylated indolyl-triazole Schiff bases for targeting breast cancer.

Nafie MS, Boraei ATA. Nafie MS, et al. Among authors: boraei ata. Bioorg Chem. 2022 May;122:105708. doi: 10.1016/j.bioorg.2022.105708. Epub 2022 Mar 8. Bioorg Chem. 2022. PMID: 35290929

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