Cochrane SA - Search Results

1

Antimicrobial lipopeptide tridecaptin A1 selectively binds to Gram-negative lipid II.

Cochrane SA, Findlay B, Bakhtiary A, Acedo JZ, Rodriguez-Lopez EM, Mercier P, Vederas JC. Cochrane SA, et al. Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):11561-11566. doi: 10.1073/pnas.1608623113. Epub 2016 Sep 29. Proc Natl Acad Sci U S A. 2016. PMID: 27688760 Free PMC article.

2

Linearization of the Brevicidine and Laterocidine Lipopeptides Yields Analogues That Retain Full Antibacterial Activity.

Ballantine RD, Al Ayed K, Bann SJ, Hoekstra M, Martin NI, Cochrane SA. Ballantine RD, et al. Among authors: cochrane sa. J Med Chem. 2023 Apr 27;66(8):6002-6009. doi: 10.1021/acs.jmedchem.3c00308. Epub 2023 Apr 18. J Med Chem. 2023. PMID: 37071814 Free PMC article.

3

Targeting membrane-bound bacterial cell wall precursors: a tried and true antibiotic strategy in nature and the clinic.

Buijs NP, Matheson EJ, Cochrane SA, Martin NI. Buijs NP, et al. Among authors: cochrane sa. Chem Commun (Camb). 2023 Jun 20;59(50):7685-7703. doi: 10.1039/d3cc01070h. Chem Commun (Camb). 2023. PMID: 37219335 Review.

4

Optimizations of lipid II synthesis: an essential glycolipid precursor in bacterial cell wall synthesis and a validated antibiotic target.

Karak M, Cloonan CR, Baker BR, Cochrane RVK, Cochrane SA. Karak M, et al. Among authors: cochrane sa. Beilstein J Org Chem. 2024 Feb 6;20:220-227. doi: 10.3762/bjoc.20.22. eCollection 2024. Beilstein J Org Chem. 2024. PMID: 38352069 Free PMC article.

5

Solid supported chemical syntheses of both components of the lantibiotic lacticin 3147.

Liu W, Chan AS, Liu H, Cochrane SA, Vederas JC. Liu W, et al. Among authors: cochrane sa. J Am Chem Soc. 2011 Sep 14;133(36):14216-9. doi: 10.1021/ja206017p. Epub 2011 Aug 17. J Am Chem Soc. 2011. PMID: 21848315

6

Investigation of the ring-closing metathesis of peptides in water.

Cochrane SA, Huang Z, Vederas JC. Cochrane SA, et al. Org Biomol Chem. 2013 Jan 28;11(4):630-9. doi: 10.1039/c2ob26938d. Epub 2012 Dec 4. Org Biomol Chem. 2013. PMID: 23212663

7

Biochemical, structural, and genetic characterization of tridecaptin A₁, an antagonist of Campylobacter jejuni.

Lohans CT, van Belkum MJ, Cochrane SA, Huang Z, Sit CS, McMullen LM, Vederas JC. Lohans CT, et al. Among authors: cochrane sa. Chembiochem. 2014 Jan 24;15(2):243-9. doi: 10.1002/cbic.201300595. Epub 2013 Dec 30. Chembiochem. 2014. PMID: 24382692

8

Synthesis and structure-activity relationship studies of N-terminal analogues of the antimicrobial peptide tridecaptin A(1).

Cochrane SA, Lohans CT, Brandelli JR, Mulvey G, Armstrong GD, Vederas JC. Cochrane SA, et al. J Med Chem. 2014 Feb 13;57(3):1127-31. doi: 10.1021/jm401779d. Epub 2014 Jan 30. J Med Chem. 2014. PMID: 24479847

9

Key residues in octyl-tridecaptin A1 analogues linked to stable secondary structures in the membrane.

Cochrane SA, Findlay B, Vederas JC, Ratemi ES. Cochrane SA, et al. Chembiochem. 2014 Jun 16;15(9):1295-9. doi: 10.1002/cbic.201402024. Epub 2014 May 9. Chembiochem. 2014. PMID: 24816483

10

Lipopeptides from Bacillus and Paenibacillus spp.: A Gold Mine of Antibiotic Candidates.

Cochrane SA, Vederas JC. Cochrane SA, et al. Med Res Rev. 2016 Jan;36(1):4-31. doi: 10.1002/med.21321. Epub 2014 May 28. Med Res Rev. 2016. PMID: 24866700 Review.

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