Levoin N - Search Results

1

Synthesis and evaluation of a 2-benzothiazolylphenylmethyl ether class of histamine H4 receptor antagonists.

Labeeuw O, Levoin N, Billot X, Danvy D, Calmels T, Krief S, Ligneau X, Berrebi-Bertrand I, Robert P, Lecomte JM, Schwartz JC, Capet M. Labeeuw O, et al. Among authors: levoin n. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5263-5266. doi: 10.1016/j.bmcl.2016.09.049. Epub 2016 Sep 19. Bioorg Med Chem Lett. 2016. PMID: 27692832

2

Synthesis and biological testing of Acyl-CoA-ketoprofen conjugates as selective irreversible inhibitors of COX-2.

Levoin N, Chrétien F, Lapicque F, Chapleur Y. Levoin N, et al. Bioorg Med Chem. 2002 Mar;10(3):753-7. doi: 10.1016/s0968-0896(01)00330-3. Bioorg Med Chem. 2002. PMID: 11814865

3

A solid phase parallel synthesis of diverse amides as dopamine D3 receptor ligands.

Jean M, Renault J, Camelin JC, Levoin N, Danvy D, Stark H, Capet M, Uriac P. Jean M, et al. Among authors: levoin n. J Enzyme Inhib Med Chem. 2008 Oct;23(5):588-92. doi: 10.1080/14756360701830023. J Enzyme Inhib Med Chem. 2008. PMID: 18608769 Free article.

4

Refined docking as a valuable tool for lead optimization: application to histamine H3 receptor antagonists.

Levoin N, Calmels T, Poupardin-Olivier O, Labeeuw O, Danvy D, Robert P, Berrebi-Bertrand I, Ganellin CR, Schunack W, Stark H, Capet M. Levoin N, et al. Arch Pharm (Weinheim). 2008 Oct;341(10):610-23. doi: 10.1002/ardp.200800042. Arch Pharm (Weinheim). 2008. PMID: 18816585

5

Synthesis and evaluation of amides surrogates of dopamine D3 receptor ligands.

Jean M, Renault J, Levoin N, Danvy D, Calmels T, Berrebi-Bertrand I, Robert P, Schwartz JC, Lecomte JM, Uriac P, Capet M. Jean M, et al. Among authors: levoin n. Bioorg Med Chem Lett. 2010 Sep 15;20(18):5376-9. doi: 10.1016/j.bmcl.2010.07.096. Epub 2010 Jul 29. Bioorg Med Chem Lett. 2010. PMID: 20708933

6

Novel and highly potent histamine H3 receptor ligands. Part 2: exploring the cyclohexylamine-based series.

Labeeuw O, Levoin N, Poupardin-Olivier O, Calmels T, Ligneau X, Berrebi-Bertrand I, Robert P, Lecomte JM, Schwartz JC, Capet M. Labeeuw O, et al. Among authors: levoin n. Bioorg Med Chem Lett. 2011 Sep 15;21(18):5384-8. doi: 10.1016/j.bmcl.2011.06.102. Epub 2011 Jun 28. Bioorg Med Chem Lett. 2011. PMID: 21783360

7

Novel and highly potent histamine H3 receptor ligands. Part 1: withdrawing of hERG activity.

Levoin N, Labeeuw O, Calmels T, Poupardin-Olivier O, Berrebi-Bertrand I, Lecomte JM, Schwartz JC, Capet M. Levoin N, et al. Bioorg Med Chem Lett. 2011 Sep 15;21(18):5378-83. doi: 10.1016/j.bmcl.2011.07.006. Epub 2011 Jul 13. Bioorg Med Chem Lett. 2011. PMID: 21802950

8

Novel and highly potent histamine H3 receptor ligands. Part 3: an alcohol function to improve the pharmacokinetic profile.

Labeeuw O, Levoin N, Poupardin-Olivier O, Calmels T, Ligneau X, Berrebi-Bertrand I, Robert P, Lecomte JM, Schwartz JC, Capet M. Labeeuw O, et al. Among authors: levoin n. Bioorg Med Chem Lett. 2013 May 1;23(9):2548-54. doi: 10.1016/j.bmcl.2013.02.118. Epub 2013 Mar 14. Bioorg Med Chem Lett. 2013. PMID: 23535326

9

Determination of the binding mode and interacting amino-acids for dibasic H3 receptor antagonists.

Levoin N, Labeeuw O, Krief S, Calmels T, Poupardin-Olivier O, Berrebi-Bertrand I, Lecomte JM, Schwartz JC, Capet M. Levoin N, et al. Bioorg Med Chem. 2013 Aug 1;21(15):4526-9. doi: 10.1016/j.bmc.2013.05.035. Epub 2013 Jun 2. Bioorg Med Chem. 2013. PMID: 23787288

10

Design, synthesis and biological evaluation of new inhibitors of Bax/Bcl-xL interaction in cancer cells.

Vo DD, Gautier F, Barillé-Nion S, Juin P, Levoin N, Grée R. Vo DD, et al. Among authors: levoin n. Bioorg Med Chem Lett. 2014 Apr 1;24(7):1758-61. doi: 10.1016/j.bmcl.2014.02.035. Epub 2014 Feb 24. Bioorg Med Chem Lett. 2014. PMID: 24602902

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