Chen Y - Search Results

1

Drug repurposing for glioblastoma based on molecular subtypes.

Chen Y, Xu R. Chen Y, et al. J Biomed Inform. 2016 Dec;64:131-138. doi: 10.1016/j.jbi.2016.09.019. Epub 2016 Sep 30. J Biomed Inform. 2016. PMID: 27697594 Free PMC article.

2

Phenome-driven disease genetics prediction toward drug discovery.

Chen Y, Li L, Zhang GQ, Xu R. Chen Y, et al. Bioinformatics. 2015 Jun 15;31(12):i276-83. doi: 10.1093/bioinformatics/btv245. Bioinformatics. 2015. PMID: 26072493 Free PMC article.

3

Combining Human Disease Genetics and Mouse Model Phenotypes towards Drug Repositioning for Parkinson's disease.

Chen Y, Cai X, Xu R. Chen Y, et al. AMIA Annu Symp Proc. 2015 Nov 5;2015:1851-60. eCollection 2015. AMIA Annu Symp Proc. 2015. PMID: 26958284 Free PMC article.

4

Towards precision medicine-based therapies for glioblastoma: interrogating human disease genomics and mouse phenotypes.

Chen Y, Gao Z, Wang B, Xu R. Chen Y, et al. BMC Genomics. 2016 Aug 22;17 Suppl 7(Suppl 7):516. doi: 10.1186/s12864-016-2908-7. BMC Genomics. 2016. PMID: 27557118 Free PMC article.

5

Phenome-based gene discovery provides information about Parkinson's disease drug targets.

Chen Y, Xu R. Chen Y, et al. BMC Genomics. 2016 Aug 31;17 Suppl 5(Suppl 5):493. doi: 10.1186/s12864-016-2820-1. BMC Genomics. 2016. PMID: 27586503 Free PMC article.

6

Comparative analysis of a novel disease phenotype network based on clinical manifestations.

Chen Y, Zhang X, Zhang GQ, Xu R. Chen Y, et al. J Biomed Inform. 2015 Feb;53:113-20. doi: 10.1016/j.jbi.2014.09.007. Epub 2014 Sep 30. J Biomed Inform. 2015. PMID: 25277758 Free PMC article.

7

Using a novel computational drug-repositioning approach (DrugPredict) to rapidly identify potent drug candidates for cancer treatment.

Nagaraj AB, Wang QQ, Joseph P, Zheng C, Chen Y, Kovalenko O, Singh S, Armstrong A, Resnick K, Zanotti K, Waggoner S, Xu R, DiFeo A. Nagaraj AB, et al. Among authors: chen y. Oncogene. 2018 Jan 18;37(3):403-414. doi: 10.1038/onc.2017.328. Epub 2017 Oct 2. Oncogene. 2018. PMID: 28967908 Free PMC article.

8

Mining cancer-specific disease comorbidities from a large observational health database.

Chen Y, Xu R. Chen Y, et al. Cancer Inform. 2014 Oct 13;13(Suppl 1):37-44. doi: 10.4137/CIN.S13893. eCollection 2014. Cancer Inform. 2014. PMID: 25392682 Free PMC article.

9

Network-based gene prediction for Plasmodium falciparum malaria towards genetics-based drug discovery.

Chen Y, Xu R. Chen Y, et al. BMC Genomics. 2015;16 Suppl 7(Suppl 7):S9. doi: 10.1186/1471-2164-16-S7-S9. Epub 2015 Jun 11. BMC Genomics. 2015. PMID: 26099491 Free PMC article.

10

Disease Comorbidity Network Guides the Detection of Molecular Evidence for the Link Between Colorectal Cancer and Obesity.

Chen Y, Li L, Xu R. Chen Y, et al. AMIA Jt Summits Transl Sci Proc. 2015 Mar 23;2015:201-6. eCollection 2015. AMIA Jt Summits Transl Sci Proc. 2015. PMID: 26306270 Free PMC article.

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