Ho CM - Search Results

1

Modelling proteins' hidden conformations to predict antibiotic resistance.

Hart KM, Ho CM, Dutta S, Gross ML, Bowman GR. Hart KM, et al. Among authors: ho cm. Nat Commun. 2016 Oct 6;7:12965. doi: 10.1038/ncomms12965. Nat Commun. 2016. PMID: 27708258 Free PMC article.

2

Designing small molecules to target cryptic pockets yields both positive and negative allosteric modulators.

Hart KM, Moeder KE, Ho CMW, Zimmerman MI, Frederick TE, Bowman GR. Hart KM, et al. PLoS One. 2017 Jun 1;12(6):e0178678. doi: 10.1371/journal.pone.0178678. eCollection 2017. PLoS One. 2017. PMID: 28570708 Free PMC article.

3

Hybrid Methods Reveal Multiple Flexibly Linked DNA Polymerases within the Bacteriophage T7 Replisome.

Wallen JR, Zhang H, Weis C, Cui W, Foster BM, Ho CMW, Hammel M, Tainer JA, Gross ML, Ellenberger T. Wallen JR, et al. Structure. 2017 Jan 3;25(1):157-166. doi: 10.1016/j.str.2016.11.019. Structure. 2017. PMID: 28052235 Free PMC article.

4

Defining NADH-Driven Allostery Regulating Apoptosis-Inducing Factor.

Brosey CA, Ho C, Long WZ, Singh S, Burnett K, Hura GL, Nix JC, Bowman GR, Ellenberger T, Tainer JA. Brosey CA, et al. Structure. 2016 Dec 6;24(12):2067-2079. doi: 10.1016/j.str.2016.09.012. Epub 2016 Nov 3. Structure. 2016. PMID: 27818101 Free PMC article.

5

Structure of mammalian poly(ADP-ribose) glycohydrolase reveals a flexible tyrosine clasp as a substrate-binding element.

Kim IK, Kiefer JR, Ho CM, Stegeman RA, Classen S, Tainer JA, Ellenberger T. Kim IK, et al. Among authors: ho cm. Nat Struct Mol Biol. 2012 May 20;19(6):653-6. doi: 10.1038/nsmb.2305. Nat Struct Mol Biol. 2012. PMID: 22609859 Free PMC article.

6

Design, synthesis, and biological evaluation of stable β^6.3-Helices: Discovery of non-hemolytic antibacterial peptides.

Reddy DN, Singh S, Ho CMW, Patel J, Schlesinger P, Rodgers S, Doctor A, Marshall GR. Reddy DN, et al. Eur J Med Chem. 2018 Apr 10;149:193-210. doi: 10.1016/j.ejmech.2018.02.057. Epub 2018 Feb 20. Eur J Med Chem. 2018. PMID: 29501941 Free PMC article.

7

PARG has a robust endo-glycohydrolase activity that releases protein-free poly(ADP-ribose) chains.

Pourfarjam Y, Kasson S, Tran L, Ho C, Lim S, Kim IK. Pourfarjam Y, et al. Biochem Biophys Res Commun. 2020 Jun 30;527(3):818-823. doi: 10.1016/j.bbrc.2020.04.120. Epub 2020 May 18. Biochem Biophys Res Commun. 2020. PMID: 32439163

8

A mechanism for lipid binding to apoE and the role of intrinsically disordered regions coupled to domain-domain interactions.

Frieden C, Wang H, Ho CMW. Frieden C, et al. Proc Natl Acad Sci U S A. 2017 Jun 13;114(24):6292-6297. doi: 10.1073/pnas.1705080114. Epub 2017 May 30. Proc Natl Acad Sci U S A. 2017. PMID: 28559318 Free PMC article.

9

Metal complexes of chiral pentaazacrowns as conformational templates for beta-turn recognition.

Reaka AJ, Ho CM, Marshall GR. Reaka AJ, et al. Among authors: ho cm. J Comput Aided Mol Des. 2002 Aug-Sep;16(8-9):585-600. doi: 10.1023/a:1021980019452. J Comput Aided Mol Des. 2002. PMID: 12602952

10

Conformationally restricted TRH analogues: constraining the pyroglutamate region.

Simpson JC, Ho C, Shands EF, Gershengorn MC, Marshall GR, Moeller KD. Simpson JC, et al. Bioorg Med Chem. 2002 Feb;10(2):291-302. doi: 10.1016/s0968-0896(01)00287-5. Bioorg Med Chem. 2002. PMID: 11741778

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