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The combination of TPL2 knockdown and TNFα causes synthetic lethality via caspase-8 activation in human carcinoma cell lines.
Serebrennikova OB, Paraskevopoulou MD, Aguado-Fraile E, Taraslia V, Ren W, Thapa G, Roper J, Du K, Croce CM, Tsichlis PN. Serebrennikova OB, et al. Among authors: ren w. Proc Natl Acad Sci U S A. 2019 Jul 9;116(28):14039-14048. doi: 10.1073/pnas.1901465116. Epub 2019 Jun 25. Proc Natl Acad Sci U S A. 2019. PMID: 31239343 Free PMC article.
Tpl2 ablation promotes intestinal inflammation and tumorigenesis in Apcmin mice by inhibiting IL-10 secretion and regulatory T-cell generation.
Serebrennikova OB, Tsatsanis C, Mao C, Gounaris E, Ren W, Siracusa LD, Eliopoulos AG, Khazaie K, Tsichlis PN. Serebrennikova OB, et al. Among authors: ren w. Proc Natl Acad Sci U S A. 2012 May 1;109(18):E1082-91. doi: 10.1073/pnas.1115098109. Epub 2012 Mar 26. Proc Natl Acad Sci U S A. 2012. PMID: 22451924 Free PMC article.
4,814 results