Sobczak K - Search Results

1

Mechanistic determinants of MBNL activity.

Sznajder ŁJ, Michalak M, Taylor K, Cywoniuk P, Kabza M, Wojtkowiak-Szlachcic A, Matłoka M, Konieczny P, Sobczak K. Sznajder ŁJ, et al. Among authors: sobczak k. Nucleic Acids Res. 2016 Dec 1;44(21):10326-10342. doi: 10.1093/nar/gkw915. Epub 2016 Oct 12. Nucleic Acids Res. 2016. PMID: 27733504 Free PMC article.

2

Muscleblind-like 1 interacts with RNA hairpins in splicing target and pathogenic RNAs.

Yuan Y, Compton SA, Sobczak K, Stenberg MG, Thornton CA, Griffith JD, Swanson MS. Yuan Y, et al. Among authors: sobczak k. Nucleic Acids Res. 2007;35(16):5474-86. doi: 10.1093/nar/gkm601. Epub 2007 Aug 15. Nucleic Acids Res. 2007. PMID: 17702765 Free PMC article.

3

CAG repeats mimic CUG repeats in the misregulation of alternative splicing.

Mykowska A, Sobczak K, Wojciechowska M, Kozlowski P, Krzyzosiak WJ. Mykowska A, et al. Among authors: sobczak k. Nucleic Acids Res. 2011 Nov 1;39(20):8938-51. doi: 10.1093/nar/gkr608. Epub 2011 Jul 27. Nucleic Acids Res. 2011. PMID: 21795378 Free PMC article.

4

Chemical correction of pre-mRNA splicing defects associated with sequestration of muscleblind-like 1 protein by expanded r(CAG)-containing transcripts.

Kumar A, Parkesh R, Sznajder LJ, Childs-Disney JL, Sobczak K, Disney MD. Kumar A, et al. Among authors: sobczak k. ACS Chem Biol. 2012 Mar 16;7(3):496-505. doi: 10.1021/cb200413a. Epub 2012 Jan 17. ACS Chem Biol. 2012. PMID: 22252896 Free PMC article.

5

RNA interference targeting CUG repeats in a mouse model of myotonic dystrophy.

Sobczak K, Wheeler TM, Wang W, Thornton CA. Sobczak K, et al. Mol Ther. 2013 Feb;21(2):380-7. doi: 10.1038/mt.2012.222. Epub 2012 Nov 27. Mol Ther. 2013. PMID: 23183533 Free PMC article.

6

Lomofungin and dilomofungin: inhibitors of MBNL1-CUG RNA binding with distinct cellular effects.

Hoskins JW, Ofori LO, Chen CZ, Kumar A, Sobczak K, Nakamori M, Southall N, Patnaik S, Marugan JJ, Zheng W, Austin CP, Disney MD, Miller BL, Thornton CA. Hoskins JW, et al. Among authors: sobczak k. Nucleic Acids Res. 2014 Jun;42(10):6591-602. doi: 10.1093/nar/gku275. Epub 2014 May 5. Nucleic Acids Res. 2014. PMID: 24799433 Free PMC article.

7

Small molecule kinase inhibitors alleviate different molecular features of myotonic dystrophy type 1.

Wojciechowska M, Taylor K, Sobczak K, Napierala M, Krzyzosiak WJ. Wojciechowska M, et al. Among authors: sobczak k. RNA Biol. 2014;11(6):742-54. doi: 10.4161/rna.28799. Epub 2014 Apr 24. RNA Biol. 2014. PMID: 24824895 Free PMC article.

8

MBNL proteins and their target RNAs, interaction and splicing regulation.

Konieczny P, Stepniak-Konieczna E, Sobczak K. Konieczny P, et al. Among authors: sobczak k. Nucleic Acids Res. 2014;42(17):10873-87. doi: 10.1093/nar/gku767. Epub 2014 Sep 2. Nucleic Acids Res. 2014. PMID: 25183524 Free PMC article. Review.

9

Loss of MBNL leads to disruption of developmentally regulated alternative polyadenylation in RNA-mediated disease.

Batra R, Charizanis K, Manchanda M, Mohan A, Li M, Finn DJ, Goodwin M, Zhang C, Sobczak K, Thornton CA, Swanson MS. Batra R, et al. Among authors: sobczak k. Mol Cell. 2014 Oct 23;56(2):311-322. doi: 10.1016/j.molcel.2014.08.027. Epub 2014 Sep 25. Mol Cell. 2014. PMID: 25263597 Free PMC article.

10

Short antisense-locked nucleic acids (all-LNAs) correct alternative splicing abnormalities in myotonic dystrophy.

Wojtkowiak-Szlachcic A, Taylor K, Stepniak-Konieczna E, Sznajder LJ, Mykowska A, Sroka J, Thornton CA, Sobczak K. Wojtkowiak-Szlachcic A, et al. Among authors: sobczak k. Nucleic Acids Res. 2015 Mar 31;43(6):3318-31. doi: 10.1093/nar/gkv163. Epub 2015 Mar 9. Nucleic Acids Res. 2015. PMID: 25753670 Free PMC article.

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