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583 results

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Page 1
Phenylindenone isomers as divergent modulators of p38α MAP kinase.
Cappelli A, Nannicini C, Chelini A, Paolino M, Giuliani G, Anzini M, Giordani A, Sabatini C, Caselli G, Mennuni L, Makovec F, Giorgi G, Vomero S, Menziani MC. Cappelli A, et al. Among authors: giorgi g. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5160-5163. doi: 10.1016/j.bmcl.2016.10.001. Epub 2016 Oct 4. Bioorg Med Chem Lett. 2016. PMID: 27746002 Free article.
Novel potent 5-HT(3) receptor ligands based on the pyrrolidone structure: synthesis, biological evaluation, and computational rationalization of the ligand-receptor interaction modalities.
Cappelli A, Anzini M, Vomero S, Mennuni L, Makovec F, Doucet E, Hamon M, Menziani MC, De Benedetti PG, Giorgi G, Ghelardini C, Collina S. Cappelli A, et al. Among authors: giorgi g. Bioorg Med Chem. 2002 Mar;10(3):779-801. doi: 10.1016/s0968-0896(01)00332-7. Bioorg Med Chem. 2002. PMID: 11814868
Design, synthesis, structural studies, biological evaluation, and computational simulations of novel potent AT(1) angiotensin II receptor antagonists based on the 4-phenylquinoline structure.
Cappelli A, Pericot Mohr Gl Gl, Gallelli A, Rizzo M, Anzini M, Vomero S, Mennuni L, Ferrari F, Makovec F, Menziani MC, De Benedetti PG, Giorgi G. Cappelli A, et al. Among authors: giorgi g. J Med Chem. 2004 May 6;47(10):2574-86. doi: 10.1021/jm031100t. J Med Chem. 2004. PMID: 15115399
Physicochemical and biopharmaceutical characterization of endo-2-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2,3-dihydro-1H-benz[e]isoindol-1-one (CR3124) a novel potent 5-HT3 receptor antagonist.
Cappelli A, Travagli V, Zanardi I, Anzini M, Giorgi G, Donati A, Aggravi M, Casolaro M, Fresta M, Paccagnini E, Makovec F, Vomero S. Cappelli A, et al. Among authors: giorgi g. J Pharm Sci. 2006 Dec;95(12):2706-21. doi: 10.1002/jps.20705. J Pharm Sci. 2006. PMID: 16924684
Further studies on imidazo[4,5-b]pyridine AT1 angiotensin II receptor antagonists. Effects of the transformation of the 4-phenylquinoline backbone into 4-phenylisoquinolinone or 1-phenylindene scaffolds.
Cappelli A, Pericot Mohr Gl, Giuliani G, Galeazzi S, Anzini M, Mennuni L, Ferrari F, Makovec F, Kleinrath EM, Langer T, Valoti M, Giorgi G, Vomero S. Cappelli A, et al. Among authors: giorgi g. J Med Chem. 2006 Nov 2;49(22):6451-64. doi: 10.1021/jm0603163. J Med Chem. 2006. PMID: 17064065
Synthesis and preliminary pharmacological evaluation of the four stereoisomers of (2S)-2-(2'-phosphono-3'-phenylcyclopropyl)glycine, the first class of 3'-substituted trans C1'-2'-2-(2'-phosphonocyclopropyl)glycines.
Marinozzi M, Serpi M, Amori L, Gavilan Diaz M, Costantino G, Meyer U, Flor PJ, Gasparini F, Heckendorn R, Kuhn R, Giorgi G, Hermit MB, Thomsen C, Pellicciari R. Marinozzi M, et al. Among authors: giorgi g. Bioorg Med Chem. 2007 May 1;15(9):3161-70. doi: 10.1016/j.bmc.2007.02.040. Epub 2007 Feb 22. Bioorg Med Chem. 2007. PMID: 17350267
583 results