Raynaud F - Search Results

1

Discovery of 4,6-disubstituted pyrimidines as potent inhibitors of the heat shock factor 1 (HSF1) stress pathway and CDK9.

Rye CS, Chessum NE, Lamont S, Pike KG, Faulder P, Demeritt J, Kemmitt P, Tucker J, Zani L, Cheeseman MD, Isaac R, Goodwin L, Boros J, Raynaud F, Hayes A, Henley AT, de Billy E, Lynch CJ, Sharp SY, Te Poele R, Fee LO, Foote KM, Green S, Workman P, Jones K. Rye CS, et al. Among authors: raynaud f. Medchemcomm. 2016 Aug 1;7(8):1580-1586. doi: 10.1039/c6md00159a. Epub 2016 Jun 13. Medchemcomm. 2016. PMID: 27746890 Free PMC article.

2

Mini-review: discovery and development of platinum complexes designed to circumvent cisplatin resistance.

Kelland LR, Sharp SY, O'Neill CF, Raynaud FI, Beale PJ, Judson IR. Kelland LR, et al. Among authors: raynaud fi. J Inorg Biochem. 1999 Oct;77(1-2):111-5. J Inorg Biochem. 1999. PMID: 10626362 Review.

3

Characterization of a human colorectal carcinoma cell line with acquired resistance to flavopiridol.

Smith V, Raynaud F, Workman P, Kelland LR. Smith V, et al. Among authors: raynaud f. Mol Pharmacol. 2001 Nov;60(5):885-93. doi: 10.1124/mol.60.5.885. Mol Pharmacol. 2001. PMID: 11641415

4

Cassette dosing pharmacokinetics of a library of 2,6,9-trisubstituted purine cyclin-dependent kinase 2 inhibitors prepared by parallel synthesis.

Raynaud FI, Fischer PM, Nutley BP, Goddard PM, Lane DP, Workman P. Raynaud FI, et al. Mol Cancer Ther. 2004 Mar;3(3):353-62. Mol Cancer Ther. 2004. PMID: 15026556

5

Evaluation of the cassette dosing approach for assessing the pharmacokinetics of geldanamycin analogues in mice.

Smith NF, Hayes A, Nutley BP, Raynaud FI, Workman P. Smith NF, et al. Among authors: raynaud fi. Cancer Chemother Pharmacol. 2004 Dec;54(6):475-86. doi: 10.1007/s00280-004-0853-7. Epub 2004 Jul 29. Cancer Chemother Pharmacol. 2004. PMID: 15526201

6

A liquid chromatographic-tandem mass spectrometric method for the determination of two selective thymidylate synthase inhibitors, BGC945 and BGC638, in mouse plasma.

Wood N, Gibbs DD, Jackman AL, Henley A, Workman P, Raynaud F. Wood N, et al. Among authors: raynaud f. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Sep 25;824(1-2):181-8. doi: 10.1016/j.jchromb.2005.07.025. J Chromatogr B Analyt Technol Biomed Life Sci. 2005. PMID: 16061428

7

Pharmacokinetic-pharmacodynamic relationships for the heat shock protein 90 molecular chaperone inhibitor 17-allylamino, 17-demethoxygeldanamycin in human ovarian cancer xenograft models.

Banerji U, Walton M, Raynaud F, Grimshaw R, Kelland L, Valenti M, Judson I, Workman P. Banerji U, et al. Among authors: raynaud f. Clin Cancer Res. 2005 Oct 1;11(19 Pt 1):7023-32. doi: 10.1158/1078-0432.CCR-05-0518. Clin Cancer Res. 2005. PMID: 16203796

8

Preclinical pharmacokinetics and metabolism of a novel diaryl pyrazole resorcinol series of heat shock protein 90 inhibitors.

Smith NF, Hayes A, James K, Nutley BP, McDonald E, Henley A, Dymock B, Drysdale MJ, Raynaud FI, Workman P. Smith NF, et al. Among authors: raynaud fi. Mol Cancer Ther. 2006 Jun;5(6):1628-37. doi: 10.1158/1535-7163.MCT-06-0041. Mol Cancer Ther. 2006. PMID: 16818523

9

Development and validation of a liquid chromatography/tandem mass spectrometry method for the determination of the novel anticancer agent 17-DMAG in human plasma.

Moreno-Farre J, Asad Y, Pacey S, Workman P, Raynaud FI. Moreno-Farre J, et al. Rapid Commun Mass Spectrom. 2006;20(19):2845-50. doi: 10.1002/rcm.2668. Rapid Commun Mass Spectrom. 2006. PMID: 16941534

10

The application of cassette dosing for pharmacokinetic screening in small-molecule cancer drug discovery.

Smith NF, Raynaud FI, Workman P. Smith NF, et al. Among authors: raynaud fi. Mol Cancer Ther. 2007 Feb;6(2):428-40. doi: 10.1158/1535-7163.MCT-06-0324. Mol Cancer Ther. 2007. PMID: 17308044 Free article. Review.

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