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Highly Effective Dual-Function Near-Infrared (NIR) Photosensitizer for Fluorescence Imaging and Photodynamic Therapy (PDT) of Cancer.
Patel N, Pera P, Joshi P, Dukh M, Tabaczynski WA, Siters KE, Kryman M, Cheruku RR, Durrani F, Missert JR, Watson R, Ohulchanskyy TY, Tracy EC, Baumann H, Pandey RK. Patel N, et al. Among authors: dukh m. J Med Chem. 2016 Nov 10;59(21):9774-9787. doi: 10.1021/acs.jmedchem.6b00890. Epub 2016 Oct 31. J Med Chem. 2016. PMID: 27749069
The Structures of Gd(III) Chelates Conjugated at the Periphery of 3-(1'-Hexyloxy)ethyl-3-devinylpyropheophorbide-a (HPPH) Have a Significant Impact on the Imaging and Therapy of Cancer.
Zhang S, Cheruku RR, Dukh M, Tabaczynski W, Patel NJ, White WH 3rd, Missert JR, Spernyak JA, Pandey RK. Zhang S, et al. Among authors: dukh m. ChemMedChem. 2020 Nov 4;15(21):2058-2070. doi: 10.1002/cmdc.202000449. Epub 2020 Oct 14. ChemMedChem. 2020. PMID: 32916033 Free PMC article.
Synthesis, Tumor Specificity, and Photosensitizing Efficacy of Erlotinib-Conjugated Chlorins and Bacteriochlorins: Identification of a Highly Effective Candidate for Photodynamic Therapy of Cancer.
Cheruku RR, Cacaccio J, Durrani FA, Tabaczynski WA, Watson R, Siters K, Missert JR, Tracy EC, Dukh M, Guru K, Koya RC, Kalinski P, Baumann H, Pandey RK. Cheruku RR, et al. Among authors: dukh m. J Med Chem. 2021 Jan 14;64(1):741-767. doi: 10.1021/acs.jmedchem.0c01735. Epub 2021 Jan 5. J Med Chem. 2021. PMID: 33400524 Free PMC article.
Photobac derived from bacteriochlorophyll-a shows potential for treating brain tumor in animal models by photodynamic therapy with desired pharmacokinetics and limited toxicity in rats and dogs.
Durrani FA, Cacaccio J, Turowski SG, Dukh M, Bshara W, Curtin L, Sexton S, Spernyak JA, Pandey RK. Durrani FA, et al. Among authors: dukh m. Biomed Pharmacother. 2023 Dec;168:115731. doi: 10.1016/j.biopha.2023.115731. Epub 2023 Oct 17. Biomed Pharmacother. 2023. PMID: 37857248 Free PMC article.
14 results