Rates SM - Search Results

1

LASSBio-1422: a new molecular scaffold with efficacy in animal models of schizophrenia and disorders of attention and cognition.

Betti AH, Antonio CB, Pompeu TE, Martins TS, Herzfeldt V, Stolz ED, Fraga CA, Barreiro E, Noël F, Rates SM. Betti AH, et al. Among authors: rates sm. Behav Pharmacol. 2017 Feb;28(1):48-62. doi: 10.1097/FBP.0000000000000267. Behav Pharmacol. 2017. PMID: 27755061

2

Serotonergic neurotransmission mediates hypothermia induced by the N-phenylpiperazine antipsychotic prototypes LASSBio-579 and LASSBio-581.

Neves G, Kliemann M, Betti AH, Conrado DJ, Tasso L, Fraga CA, Barreiro EJ, Teresa Dalla Costa, Rates SM. Neves G, et al. Among authors: rates sm. Pharmacol Biochem Behav. 2008 Mar;89(1):23-30. doi: 10.1016/j.pbb.2007.10.018. Epub 2007 Nov 6. Pharmacol Biochem Behav. 2008. PMID: 18082872

3

Searching for multi-target antipsychotics: Discovery of orally active heterocyclic N-phenylpiperazine ligands of D2-like and 5-HT1A receptors.

Neves G, Menegatti R, Antonio CB, Grazziottin LR, Vieira RO, Rates SM, Noël F, Barreiro EJ, Fraga CA. Neves G, et al. Among authors: rates sm. Bioorg Med Chem. 2010 Mar 1;18(5):1925-35. doi: 10.1016/j.bmc.2010.01.040. Epub 2010 Jan 25. Bioorg Med Chem. 2010. PMID: 20153652 Free article.

4

New insights into pharmacological profile of LASSBio-579, a multi-target N-phenylpiperazine derivative active on animal models of schizophrenia.

Neves G, Antonio CB, Betti AH, Pranke MA, Fraga CA, Barreiro EJ, Noël F, Rates SM. Neves G, et al. Among authors: rates sm. Behav Brain Res. 2013 Jan 15;237:86-95. doi: 10.1016/j.bbr.2012.09.016. Epub 2012 Sep 19. Behav Brain Res. 2013. PMID: 23000351

5

Synthesis and pharmacological evaluation of new N-phenylpiperazine derivatives designed as homologues of the antipsychotic lead compound LASSBio-579.

Pompeu TE, Alves FR, Figueiredo CD, Antonio CB, Herzfeldt V, Moura BC, Rates SM, Barreiro EJ, Fraga CA, Noël F. Pompeu TE, et al. Among authors: rates sm. Eur J Med Chem. 2013 Aug;66:122-34. doi: 10.1016/j.ejmech.2013.05.027. Epub 2013 May 30. Eur J Med Chem. 2013. PMID: 23792350

6

LASSBio-579, a prototype antipsychotic drug, and clozapine are effective in novel object recognition task, a recognition memory model.

Antonio CB, Betti AH, Herzfeldt V, Barreiro EJ, Fraga CA, Rates SM. Antonio CB, et al. Among authors: rates sm. Behav Pharmacol. 2016 Jun;27(4):339-49. doi: 10.1097/FBP.0000000000000200. Behav Pharmacol. 2016. PMID: 26513177

7

Design, synthesis and pharmacological profile of novel dopamine D2 receptor ligands.

Menegatti R, Cunha AC, Ferreira VF, Perreira EF, El-Nabawi A, Eldefrawi AT, Albuquerque EX, Neves G, Rates SM, Fraga CA, Barreiro EJ. Menegatti R, et al. Among authors: rates sm. Bioorg Med Chem. 2003 Nov 3;11(22):4807-13. doi: 10.1016/s0968-0896(03)00487-5. Bioorg Med Chem. 2003. PMID: 14556797

8

Design of new dopamine D2 receptor ligands: biosynthesis and pharmacological evaluation of the hydroxylated metabolite of LASSBio-581.

Pazini F, Menegatti R, Sabino JR, Andrade CH, Neves G, Rates SM, Noël F, Fraga CA, Barreiro EJ, de Oliveira V. Pazini F, et al. Among authors: rates sm. Bioorg Med Chem Lett. 2010 May 1;20(9):2888-91. doi: 10.1016/j.bmcl.2010.03.034. Epub 2010 Mar 10. Bioorg Med Chem Lett. 2010. PMID: 20363131

9

Uliginosin B, a phloroglucinol derivative from Hypericum polyanthemum: a promising new molecular pattern for the development of antidepressant drugs.

Stein AC, Viana AF, Müller LG, Nunes JM, Stolz ED, Do Rego JC, Costentin J, von Poser GL, Rates SM. Stein AC, et al. Among authors: rates sm. Behav Brain Res. 2012 Mar 1;228(1):66-73. doi: 10.1016/j.bbr.2011.11.031. Epub 2011 Dec 2. Behav Brain Res. 2012. PMID: 22155486

10

Biotransformation of LASSBio-579 and pharmacological evaluation of p-hydroxylated metabolite a N-phenylpiperazine antipsychotic lead compound.

Gomes TF, Pompeu TE, Rodrigues DA, Noël F, Menegatti R, Andrade CH, Sabino JR, Gil ES, Dalla Costa T, Betti AH, Antonio CB, Rates SM, Fraga CA, Barreiro EJ, de Oliveira V. Gomes TF, et al. Among authors: rates sm. Eur J Med Chem. 2013 Apr;62:214-21. doi: 10.1016/j.ejmech.2012.08.011. Epub 2012 Aug 20. Eur J Med Chem. 2013. PMID: 23353740

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