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Cisplatin-induced synthetic lethality to arginine-starvation therapy by transcriptional suppression of ASS1 is regulated by DEC1, HIF-1α, and c-Myc transcription network and is independent of ASS1 promoter DNA methylation.
Long Y, Tsai WB, Chang JT, Estecio M, Wangpaichitr M, Savaraj N, Feun LG, Chen HH, Kuo MT. Long Y, et al. Among authors: tsai wb. Oncotarget. 2016 Dec 13;7(50):82658-82670. doi: 10.18632/oncotarget.12308. Oncotarget. 2016. PMID: 27765932 Free PMC article.
Mechanistic basis for overcoming platinum resistance using copper chelating agents.
Liang ZD, Long Y, Tsai WB, Fu S, Kurzrock R, Gagea-Iurascu M, Zhang F, Chen HH, Hennessy BT, Mills GB, Savaraj N, Kuo MT. Liang ZD, et al. Among authors: tsai wb. Mol Cancer Ther. 2012 Nov;11(11):2483-94. doi: 10.1158/1535-7163.MCT-12-0580. Epub 2012 Aug 21. Mol Cancer Ther. 2012. PMID: 22914438 Free PMC article.
Targeting drug transport mechanisms for improving platinum-based cancer chemotherapy.
Chen HH, Chen WC, Liang ZD, Tsai WB, Long Y, Aiba I, Fu S, Broaddus R, Liu J, Feun LG, Savaraj N, Kuo MT. Chen HH, et al. Among authors: tsai wb. Expert Opin Ther Targets. 2015;19(10):1307-17. doi: 10.1517/14728222.2015.1043269. Epub 2015 May 25. Expert Opin Ther Targets. 2015. PMID: 26004625 Free PMC article. Review.
Gas6/Axl in arginine-starvation therapy.
Tsai WB, Long Y, Kuo MT. Tsai WB, et al. Oncoscience. 2015 Aug 25;2(8):659-60. doi: 10.18632/oncoscience.218. eCollection 2015. Oncoscience. 2015. PMID: 26425646 Free PMC article. No abstract available.
135 results