Huntington JA - Search Results

1

Design and characterization of an APC-specific serpin for the treatment of hemophilia.

Polderdijk SG, Adams TE, Ivanciu L, Camire RM, Baglin TP, Huntington JA. Polderdijk SG, et al. Among authors: huntington ja. Blood. 2017 Jan 5;129(1):105-113. doi: 10.1182/blood-2016-05-718635. Epub 2016 Oct 27. Blood. 2017. PMID: 27789479 Free PMC article.

2

Crystal structure of the prothrombinase complex from the venom of Pseudonaja textilis.

Lechtenberg BC, Murray-Rust TA, Johnson DJ, Adams TE, Krishnaswamy S, Camire RM, Huntington JA. Lechtenberg BC, et al. Among authors: huntington ja. Blood. 2013 Oct 17;122(16):2777-83. doi: 10.1182/blood-2013-06-511733. Epub 2013 Jul 18. Blood. 2013. PMID: 23869089 Free PMC article.

3

A hereditary bleeding disorder resulting from a premature stop codon in thrombomodulin (p.Cys537Stop).

Langdown J, Luddington RJ, Huntington JA, Baglin TP. Langdown J, et al. Among authors: huntington ja. Blood. 2014 Sep 18;124(12):1951-6. doi: 10.1182/blood-2014-02-557538. Epub 2014 Jul 21. Blood. 2014. PMID: 25049278 Free PMC article.

4

Targeting activated protein C to treat hemophilia.

Polderdijk SGI, Baglin TP, Huntington JA. Polderdijk SGI, et al. Among authors: huntington ja. Curr Opin Hematol. 2017 Sep;24(5):446-452. doi: 10.1097/MOH.0000000000000364. Curr Opin Hematol. 2017. PMID: 28632502 Free PMC article. Review.

5

Identification of serpins specific for activated protein C using a lysate-based screening assay.

Polderdijk SGI, Huntington JA. Polderdijk SGI, et al. Among authors: huntington ja. Sci Rep. 2018 Jun 8;8(1):8793. doi: 10.1038/s41598-018-27067-z. Sci Rep. 2018. PMID: 29884816 Free PMC article.

6

Crystal structures of native and thrombin-complexed heparin cofactor II reveal a multistep allosteric mechanism.

Baglin TP, Carrell RW, Church FC, Esmon CT, Huntington JA. Baglin TP, et al. Among authors: huntington ja. Proc Natl Acad Sci U S A. 2002 Aug 20;99(17):11079-84. doi: 10.1073/pnas.162232399. Epub 2002 Aug 8. Proc Natl Acad Sci U S A. 2002. PMID: 12169660 Free PMC article.

7

Targeting thrombin--rational drug design from natural mechanisms.

Huntington JA, Baglin TP. Huntington JA, et al. Trends Pharmacol Sci. 2003 Nov;24(11):589-95. doi: 10.1016/j.tips.2003.09.002. Trends Pharmacol Sci. 2003. PMID: 14607082 Review.

8

Allosteric activation of antithrombin critically depends upon hinge region extension.

Langdown J, Johnson DJ, Baglin TP, Huntington JA. Langdown J, et al. Among authors: huntington ja. J Biol Chem. 2004 Nov 5;279(45):47288-97. doi: 10.1074/jbc.M408961200. Epub 2004 Aug 23. J Biol Chem. 2004. PMID: 15326167 Free article.

9

Antithrombin-S195A factor Xa-heparin structure reveals the allosteric mechanism of antithrombin activation.

Johnson DJ, Li W, Adams TE, Huntington JA. Johnson DJ, et al. Among authors: huntington ja. EMBO J. 2006 May 3;25(9):2029-37. doi: 10.1038/sj.emboj.7601089. Epub 2006 Apr 13. EMBO J. 2006. PMID: 16619025 Free PMC article.

10

Molecular basis of thrombin recognition by protein C inhibitor revealed by the 1.6-A structure of the heparin-bridged complex.

Li W, Adams TE, Nangalia J, Esmon CT, Huntington JA. Li W, et al. Among authors: huntington ja. Proc Natl Acad Sci U S A. 2008 Mar 25;105(12):4661-6. doi: 10.1073/pnas.0711055105. Epub 2008 Mar 24. Proc Natl Acad Sci U S A. 2008. PMID: 18362344 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

139 results

Search Page

Filters