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A zymogen-like factor Xa variant corrects the coagulation defect in hemophilia.
Ivanciu L, Toso R, Margaritis P, Pavani G, Kim H, Schlachterman A, Liu JH, Clerin V, Pittman DD, Rose-Miranda R, Shields KM, Erbe DV, Tobin JF, Arruda VR, Camire RM. Ivanciu L, et al. Nat Biotechnol. 2011 Oct 23;29(11):1028-33. doi: 10.1038/nbt.1995. Nat Biotechnol. 2011. PMID: 22020385 Free PMC article.
Imaging coagulation reactions in vivo.
Ivanciu L, Krishnaswamy S, Camire RM. Ivanciu L, et al. Thromb Res. 2012 May;129 Suppl 2(Suppl 2):S54-6. doi: 10.1016/j.thromres.2012.02.034. Epub 2012 Mar 8. Thromb Res. 2012. PMID: 22405051 Free PMC article. Review.
An RNAi therapeutic targeting antithrombin to rebalance the coagulation system and promote hemostasis in hemophilia.
Sehgal A, Barros S, Ivanciu L, Cooley B, Qin J, Racie T, Hettinger J, Carioto M, Jiang Y, Brodsky J, Prabhala H, Zhang X, Attarwala H, Hutabarat R, Foster D, Milstein S, Charisse K, Kuchimanchi S, Maier MA, Nechev L, Kandasamy P, Kel'in AV, Nair JK, Rajeev KG, Manoharan M, Meyers R, Sorensen B, Simon AR, Dargaud Y, Negrier C, Camire RM, Akinc A. Sehgal A, et al. Among authors: ivanciu l. Nat Med. 2015 May;21(5):492-7. doi: 10.1038/nm.3847. Epub 2015 Apr 13. Nat Med. 2015. PMID: 25849132
AAV capsid CD8+ T-cell epitopes are highly conserved across AAV serotypes.
Hui DJ, Edmonson SC, Podsakoff GM, Pien GC, Ivanciu L, Camire RM, Ertl H, Mingozzi F, High KA, Basner-Tschakarjan E. Hui DJ, et al. Among authors: ivanciu l. Mol Ther Methods Clin Dev. 2015 Sep 30;2:15029. doi: 10.1038/mtm.2015.29. eCollection 2015. Mol Ther Methods Clin Dev. 2015. PMID: 26445723 Free PMC article.
30 results