Dervan PB - Search Results

1

RNA polymerase II senses obstruction in the DNA minor groove via a conserved sensor motif.

Xu L, Wang W, Gotte D, Yang F, Hare AA, Welch TR, Li BC, Shin JH, Chong J, Strathern JN, Dervan PB, Wang D. Xu L, et al. Among authors: dervan pb. Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):12426-12431. doi: 10.1073/pnas.1612745113. Epub 2016 Oct 17. Proc Natl Acad Sci U S A. 2016. PMID: 27791148 Free PMC article.

2

Modulation of NF-κB-dependent gene transcription using programmable DNA minor groove binders.

Raskatov JA, Meier JL, Puckett JW, Yang F, Ramakrishnan P, Dervan PB. Raskatov JA, et al. Among authors: dervan pb. Proc Natl Acad Sci U S A. 2012 Jan 24;109(4):1023-8. doi: 10.1073/pnas.1118506109. Epub 2011 Dec 27. Proc Natl Acad Sci U S A. 2012. PMID: 22203967 Free PMC article.

3

Antitumor activity of a pyrrole-imidazole polyamide.

Yang F, Nickols NG, Li BC, Marinov GK, Said JW, Dervan PB. Yang F, et al. Among authors: dervan pb. Proc Natl Acad Sci U S A. 2013 Jan 29;110(5):1863-8. doi: 10.1073/pnas.1222035110. Epub 2013 Jan 14. Proc Natl Acad Sci U S A. 2013. PMID: 23319609 Free PMC article.

4

Structural basis for the initiation of eukaryotic transcription-coupled DNA repair.

Xu J, Lahiri I, Wang W, Wier A, Cianfrocco MA, Chong J, Hare AA, Dervan PB, DiMaio F, Leschziner AE, Wang D. Xu J, et al. Among authors: dervan pb. Nature. 2017 Nov 30;551(7682):653-657. doi: 10.1038/nature24658. Epub 2017 Nov 22. Nature. 2017. PMID: 29168508 Free PMC article.

5

RNA polymerase II trapped on a molecular treadmill: Structural basis of persistent transcriptional arrest by a minor groove DNA binder.

Oh J, Jia T, Xu J, Chong J, Dervan PB, Wang D. Oh J, et al. Among authors: dervan pb. Proc Natl Acad Sci U S A. 2022 Jan 18;119(3):e2114065119. doi: 10.1073/pnas.2114065119. Proc Natl Acad Sci U S A. 2022. PMID: 35022237 Free PMC article.

6

DNA sequence selectivity of hairpin polyamide turn units.

Farkas ME, Li BC, Dose C, Dervan PB. Farkas ME, et al. Among authors: dervan pb. Bioorg Med Chem Lett. 2009 Jul 15;19(14):3919-23. doi: 10.1016/j.bmcl.2009.03.072. Epub 2009 Mar 24. Bioorg Med Chem Lett. 2009. PMID: 19349175 Free PMC article.

7

Synthesis of cyclic Py-Im polyamide libraries.

Li BC, Montgomery DC, Puckett JW, Dervan PB. Li BC, et al. Among authors: dervan pb. J Org Chem. 2013 Jan 4;78(1):124-33. doi: 10.1021/jo302053v. Epub 2012 Nov 2. J Org Chem. 2013. PMID: 23106218 Free PMC article.

8

Animal toxicity of hairpin pyrrole-imidazole polyamides varies with the turn unit.

Yang F, Nickols NG, Li BC, Szablowski JO, Hamilton SR, Meier JL, Wang CM, Dervan PB. Yang F, et al. Among authors: dervan pb. J Med Chem. 2013 Sep 26;56(18):7449-57. doi: 10.1021/jm401100s. Epub 2013 Sep 9. J Med Chem. 2013. PMID: 24015881 Free PMC article.

9

Tumor Repression of VCaP Xenografts by a Pyrrole-Imidazole Polyamide.

Hargrove AE, Martinez TF, Hare AA, Kurmis AA, Phillips JW, Sud S, Pienta KJ, Dervan PB. Hargrove AE, et al. Among authors: dervan pb. PLoS One. 2015 Nov 16;10(11):e0143161. doi: 10.1371/journal.pone.0143161. eCollection 2015. PLoS One. 2015. PMID: 26571387 Free PMC article.

10

A Pyrrole-Imidazole Polyamide Is Active against Enzalutamide-Resistant Prostate Cancer.

Kurmis AA, Yang F, Welch TR, Nickols NG, Dervan PB. Kurmis AA, et al. Among authors: dervan pb. Cancer Res. 2017 May 1;77(9):2207-2212. doi: 10.1158/0008-5472.CAN-16-2503. Epub 2017 Mar 30. Cancer Res. 2017. PMID: 28360139 Free PMC article.

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