Holehouse AS - Search Results

1

Sequence Determinants of the Conformational Properties of an Intrinsically Disordered Protein Prior to and upon Multisite Phosphorylation.

Martin EW, Holehouse AS, Grace CR, Hughes A, Pappu RV, Mittag T. Martin EW, et al. Among authors: holehouse as. J Am Chem Soc. 2016 Nov 30;138(47):15323-15335. doi: 10.1021/jacs.6b10272. Epub 2016 Nov 17. J Am Chem Soc. 2016. PMID: 27807972 Free PMC article.

2

Quantitative assessments of the distinct contributions of polypeptide backbone amides versus side chain groups to chain expansion via chemical denaturation.

Holehouse AS, Garai K, Lyle N, Vitalis A, Pappu RV. Holehouse AS, et al. J Am Chem Soc. 2015 Mar 4;137(8):2984-95. doi: 10.1021/ja512062h. Epub 2015 Feb 23. J Am Chem Soc. 2015. PMID: 25664638 Free PMC article.

3

Protein polymers: Encoding phase transitions.

Holehouse AS, Pappu RV. Holehouse AS, et al. Nat Mater. 2015 Nov;14(11):1083-4. doi: 10.1038/nmat4459. Nat Mater. 2015. PMID: 26490213 No abstract available.

4

Sequence Determinants of Intracellular Phase Separation by Complex Coacervation of a Disordered Protein.

Pak CW, Kosno M, Holehouse AS, Padrick SB, Mittal A, Ali R, Yunus AA, Liu DR, Pappu RV, Rosen MK. Pak CW, et al. Among authors: holehouse as. Mol Cell. 2016 Jul 7;63(1):72-85. doi: 10.1016/j.molcel.2016.05.042. Mol Cell. 2016. PMID: 27392146 Free PMC article.

5

CIDER: Resources to Analyze Sequence-Ensemble Relationships of Intrinsically Disordered Proteins.

Holehouse AS, Das RK, Ahad JN, Richardson MO, Pappu RV. Holehouse AS, et al. Biophys J. 2017 Jan 10;112(1):16-21. doi: 10.1016/j.bpj.2016.11.3200. Biophys J. 2017. PMID: 28076807 Free PMC article.

6

Evolutionary fine-tuning of conformational ensembles in FimH during host-pathogen interactions.

Kalas V, Pinkner JS, Hannan TJ, Hibbing ME, Dodson KW, Holehouse AS, Zhang H, Tolia NH, Gross ML, Pappu RV, Janetka J, Hultgren SJ. Kalas V, et al. Among authors: holehouse as. Sci Adv. 2017 Feb 10;3(2):e1601944. doi: 10.1126/sciadv.1601944. eCollection 2017 Feb. Sci Adv. 2017. PMID: 28246638 Free PMC article.

7

To Mix, or To Demix, That Is the Question.

Harmon TS, Holehouse AS, Pappu RV. Harmon TS, et al. Among authors: holehouse as. Biophys J. 2017 Feb 28;112(4):565-567. doi: 10.1016/j.bpj.2016.12.031. Biophys J. 2017. PMID: 28256216 Free PMC article. No abstract available.

8

FUS Zigzags Its Way to Cross Beta.

Holehouse AS, Pappu RV. Holehouse AS, et al. Cell. 2017 Oct 19;171(3):499-500. doi: 10.1016/j.cell.2017.10.007. Cell. 2017. PMID: 29053965 Free article.

9

Phase behaviour of disordered proteins underlying low density and high permeability of liquid organelles.

Wei MT, Elbaum-Garfinkle S, Holehouse AS, Chen CC, Feric M, Arnold CB, Priestley RD, Pappu RV, Brangwynne CP. Wei MT, et al. Among authors: holehouse as. Nat Chem. 2017 Nov;9(11):1118-1125. doi: 10.1038/nchem.2803. Epub 2017 Jun 26. Nat Chem. 2017. PMID: 29064502 Free PMC article.

10

Intrinsically disordered linkers determine the interplay between phase separation and gelation in multivalent proteins.

Harmon TS, Holehouse AS, Rosen MK, Pappu RV. Harmon TS, et al. Among authors: holehouse as. Elife. 2017 Nov 1;6:e30294. doi: 10.7554/eLife.30294. Elife. 2017. PMID: 29091028 Free PMC article.

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