Poulsen SA - Search Results

1

P-glycoprotein-mediated chemoresistance is reversed by carbonic anhydrase XII inhibitors.

Kopecka J, Rankin GM, Salaroglio IC, Poulsen SA, Riganti C. Kopecka J, et al. Among authors: poulsen sa. Oncotarget. 2016 Dec 27;7(52):85861-85875. doi: 10.18632/oncotarget.13040. Oncotarget. 2016. PMID: 27811376 Free PMC article.

2

Synthesis and structure-activity relationships of novel benzene sulfonamides with potent binding affinity for bovine carbonic anhydrase II.

Poulsen SA, Bornaghi LF, Healy PC. Poulsen SA, et al. Bioorg Med Chem Lett. 2005 Dec 15;15(24):5429-33. doi: 10.1016/j.bmcl.2005.08.113. Epub 2005 Oct 6. Bioorg Med Chem Lett. 2005. PMID: 16213706

3

Fragment-based drug discovery of carbonic anhydrase II inhibitors by dynamic combinatorial chemistry utilizing alkene cross metathesis.

Poulsen SA, Bornaghi LF. Poulsen SA, et al. Bioorg Med Chem. 2006 May 15;14(10):3275-84. doi: 10.1016/j.bmc.2005.12.054. Epub 2006 Jan 20. Bioorg Med Chem. 2006. PMID: 16431113 Free article.

4

A novel class of carbonic anhydrase inhibitors: glycoconjugate benzene sulfonamides prepared by "click-tailing".

Wilkinson BL, Bornaghi LF, Houston TA, Innocenti A, Supuran CT, Poulsen SA. Wilkinson BL, et al. Among authors: poulsen sa. J Med Chem. 2006 Nov 2;49(22):6539-48. doi: 10.1021/jm060967z. J Med Chem. 2006. PMID: 17064072 Free article.

5

Inhibition of membrane-associated carbonic anhydrase isozymes IX, XII and XIV with a library of glycoconjugate benzenesulfonamides.

Wilkinson BL, Bornaghi LF, Houston TA, Innocenti A, Vullo D, Supuran CT, Poulsen SA. Wilkinson BL, et al. Among authors: poulsen sa. Bioorg Med Chem Lett. 2007 Feb 15;17(4):987-92. doi: 10.1016/j.bmcl.2006.11.046. Epub 2006 Nov 17. Bioorg Med Chem Lett. 2007. PMID: 17157501 Free article.

6

Carbonic anhydrase inhibitors: inhibition of isozymes I, II, and IX with triazole-linked O-glycosides of benzene sulfonamides.

Wilkinson BL, Bornaghi LF, Houston TA, Innocenti A, Vullo D, Supuran CT, Poulsen SA. Wilkinson BL, et al. Among authors: poulsen sa. J Med Chem. 2007 Apr 5;50(7):1651-7. doi: 10.1021/jm061320h. Epub 2007 Mar 8. J Med Chem. 2007. PMID: 17343373

7

Inhibition of carbonic anhydrase isozymes I, II and IX with benzenesulfonamides containing an organometallic moiety.

Salmon AJ, Williams ML, Innocenti A, Vullo D, Supuran CT, Poulsen SA. Salmon AJ, et al. Among authors: poulsen sa. Bioorg Med Chem Lett. 2007 Sep 15;17(18):5032-5. doi: 10.1016/j.bmcl.2007.07.024. Epub 2007 Jul 19. Bioorg Med Chem Lett. 2007. PMID: 17681760

8

Inhibition of carbonic anhydrase isozymes with benzene sulfonamides incorporating thio, sulfinyl and sulfonyl glycoside moieties.

Singer M, Lopez M, Bornaghi LF, Innocenti A, Vullo D, Supuran CT, Poulsen SA. Singer M, et al. Among authors: poulsen sa. Bioorg Med Chem Lett. 2009 Apr 15;19(8):2273-6. doi: 10.1016/j.bmcl.2009.02.086. Epub 2009 Feb 26. Bioorg Med Chem Lett. 2009. PMID: 19286378 Free article.

9

Novel organometallic cationic ruthenium(II) pentamethylcyclopentadienyl benzenesulfonamide complexes targeted to inhibit carbonic anhydrase.

Loughrey BT, Williams ML, Healy PC, Innocenti A, Vullo D, Supuran CT, Parsons PG, Poulsen SA. Loughrey BT, et al. Among authors: poulsen sa. J Biol Inorg Chem. 2009 Aug;14(6):935-45. doi: 10.1007/s00775-009-0506-8. Epub 2009 Apr 24. J Biol Inorg Chem. 2009. PMID: 19390880

10

S-glycosyl primary sulfonamides--a new structural class for selective inhibition of cancer-associated carbonic anhydrases.

Lopez M, Paul B, Hofmann A, Morizzi J, Wu QK, Charman SA, Innocenti A, Vullo D, Supuran CT, Poulsen SA. Lopez M, et al. Among authors: poulsen sa. J Med Chem. 2009 Oct 22;52(20):6421-32. doi: 10.1021/jm900914e. J Med Chem. 2009. PMID: 19827837

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